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Epidemiology and Control of Neosporosis and Neospora caninum

TLDR
This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated.
Abstract
Neospora caninum is a protozoan parasite of animals. Until 1988, it was misidentified as Toxoplasma gondii. Since its first recognition in dogs in 1984 and the description of the new genus and species Neospora caninum in 1988, neosporosis has emerged as a serious disease of cattle and dogs worldwide. Abortions and neonatal mortality are a major problem in livestock operations, and neosporosis is a major cause of abortion in cattle. Although antibodies to N. caninum have been reported, the parasite has not been detected in human tissues. Thus, the zoonotic potential is uncertain. This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated. The role of wildlife in the life cycle of N. caninum and strategies for the control of neosporosis in cattle are discussed.

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Journal ArticleDOI

Neosporosis in Beagle dogs: Clinical signs, diagnosis, treatment, isolation and genetic characterization of Neospora caninum

TL;DR: Results indicate that medication with Clindamycin can improve clinical condition but not eliminate N. caninum infection in pups born to a Beagle bitch from Virginia, USA.
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Seroprevalence and risk factors associated with Neospora caninum infection in different dog populations in Spain.

TL;DR: It is confirmed that farm, stray and hunting dogs can be considered at-risk dog populations for N. caninum infection in Spain and horizontal transmission may be the most important route of infection.
Journal ArticleDOI

Vaccines against a Major Cause of Abortion in Cattle, Neospora caninum Infection

TL;DR: The efforts to develop a vaccine against neosporosis, caused by the apicomplexan parasite Neospora caninum, represents one of the economically most important causes of abortion in cattle.
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Pathogens of Wild Maned Wolves (Chrysocyon brachyurus) in Brazil

TL;DR: The findings highlight that canine pathogens pose a serious hazard to the viability of maned wolves and other wild carnivore populations in the area and emphasize the need for monitoring and protecting wildlife health in remaining fragments of the Cerrado biome.
Journal ArticleDOI

Risk factors associated with Neospora caninum seropositivity in randomly sampled Canadian dairy cows and herds.

TL;DR: In this paper, the authors determine cow- and herd-level risk factors associated with seropositivity for Neospora caninum in a large number of randomly selected Canadian dairy herds, controlling for important confounding variables and co-infections with bovine leukemia virus (BLV), Bovine viral diarrhea virus (BVDV) and Mycobacterium avium subspecies paratuberculosis (MAP).
References
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Journal ArticleDOI

Dogs are definitive hosts of Neospora caninum.

TL;DR: Dogs are a definitive host of Neospora caninum, and mice inoculated with canine faecal extracts were monitored for evidence of neosporosis using a variety of morphologic, immunohistologic, serologic, and genetic analyses.
Journal ArticleDOI

A review of Neospora caninum and neosporosis

TL;DR: Neospora caninum is a recently recognized protozoan parasite of animals, which until 1988 was misidentified as Toxoplasma gondii, and its life cycle is unknown.
Journal Article

Newly recognized fatal protozoan disease of dogs

TL;DR: A newly identified parasite, Neospora caninum, structurally distinct from T gondii, was found in 10 dogs and formed meronts in many tissues of the dogs, especially the brain and spinal cord.
Journal ArticleDOI

Review of Neospora caninum and neosporosis in animals.

TL;DR: Information on biology, diagnosis, epidemiology and control of neosporosis in animals, a major cause of abortion in cattle in many countries, is reviewed.
Journal Article

Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission.

TL;DR: Neospora caninum infection was diagnosed in 5 young dogs from 2 litters with a common parentage that developed hind limb paresis 5 to 8 weeks after birth and was isolated in cell cultures, mice, and dogs inoculated with infected canine tissues.
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