Epidemiology and Control of Neosporosis and Neospora caninum
TLDR
This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated.Abstract:
Neospora caninum is a protozoan parasite of animals. Until 1988, it was misidentified as Toxoplasma gondii. Since its first recognition in dogs in 1984 and the description of the new genus and species Neospora caninum in 1988, neosporosis has emerged as a serious disease of cattle and dogs worldwide. Abortions and neonatal mortality are a major problem in livestock operations, and neosporosis is a major cause of abortion in cattle. Although antibodies to N. caninum have been reported, the parasite has not been detected in human tissues. Thus, the zoonotic potential is uncertain. This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated. The role of wildlife in the life cycle of N. caninum and strategies for the control of neosporosis in cattle are discussed.read more
Citations
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Molecular detection of Neospora caninum from naturally infected dogs in Lorestan province, West of Iran
TL;DR: A polymerase chain reaction (PCR) targeting N. caninum specific Nc5 genomic fragment was performed to identify the N.Caninum DNA in the feces of naturally infected dogs of Lorestan province, West Iran and 9 positive samples of N.caninum were detected by PCR from 428 fecal specimens.
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Proteomic Characterization of Host-Pathogen Interactions during Bovine Trophoblast Cell Line Infection by Neospora caninum.
Javier Regidor-Cerrillo,Dong Xia,Laura Jiménez-Pelayo,Marta García-Sánchez,Esther Collantes-Fernández,Nadine Randle,Jonathan M. Wastling,Luis Miguel Ortega-Mora,Pilar Horcajo +8 more
TL;DR: The results showed that mitochondrial processes and metabolism were the main points of Neospora-host interactions, and Interestingly, Nc-Spain1H infection showed a higher level of influence on the host cell proteome than N c-Spain7 infection.
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Survey for the presence of Neospora caninum in frozen bull's semen samples by PCR assay
TL;DR: Evaluated the occurrence of Neospora caninum DNA using polymerase chain reaction (PCR) technique in frozen semen samples of Iranian bulls that were used for artificial insemination.
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Secretory Nanoparticles of Neospora caninum Profilin-Fused with the Transmembrane Domain of GP64 from Silkworm Hemolymph
TL;DR: Results suggest that profilin fused with GP64TM was secreted as a nanoparticle with binding affinity to its receptor and this nanoparticle formation is advantageous for the development of vaccines to N. caninum.
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Seroprevalence of Neospora caninum-specific antibodies in German breeding bitches.
Rodolfo Villagra-Blanco,Lora Angelova,Theresa Conze,Gereon Schares,Andrea Bärwald,Anja Taubert,Carlos Hermosilla,Axel Wehrend +7 more
TL;DR: Although the results confirmed a low incidence of N. caninum seropositive German breeding bitches, further epidemiological and surveillance studies are required to complement the findings regarding the current situation of neosporosis in this specific canine population of Germany.
References
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Dogs are definitive hosts of Neospora caninum.
Milton M. McAllister,Jitender P. Dubey,David S. Lindsay,Jolley Wr,Rebecca A Wills,McGuire Am +5 more
TL;DR: Dogs are a definitive host of Neospora caninum, and mice inoculated with canine faecal extracts were monitored for evidence of neosporosis using a variety of morphologic, immunohistologic, serologic, and genetic analyses.
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A review of Neospora caninum and neosporosis
TL;DR: Neospora caninum is a recently recognized protozoan parasite of animals, which until 1988 was misidentified as Toxoplasma gondii, and its life cycle is unknown.
Journal Article
Newly recognized fatal protozoan disease of dogs
TL;DR: A newly identified parasite, Neospora caninum, structurally distinct from T gondii, was found in 10 dogs and formed meronts in many tissues of the dogs, especially the brain and spinal cord.
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Review of Neospora caninum and neosporosis in animals.
TL;DR: Information on biology, diagnosis, epidemiology and control of neosporosis in animals, a major cause of abortion in cattle in many countries, is reviewed.
Journal Article
Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission.
TL;DR: Neospora caninum infection was diagnosed in 5 young dogs from 2 litters with a common parentage that developed hind limb paresis 5 to 8 weeks after birth and was isolated in cell cultures, mice, and dogs inoculated with infected canine tissues.