Epidemiology and Control of Neosporosis and Neospora caninum
TLDR
This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated.Abstract:
Neospora caninum is a protozoan parasite of animals. Until 1988, it was misidentified as Toxoplasma gondii. Since its first recognition in dogs in 1984 and the description of the new genus and species Neospora caninum in 1988, neosporosis has emerged as a serious disease of cattle and dogs worldwide. Abortions and neonatal mortality are a major problem in livestock operations, and neosporosis is a major cause of abortion in cattle. Although antibodies to N. caninum have been reported, the parasite has not been detected in human tissues. Thus, the zoonotic potential is uncertain. This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated. The role of wildlife in the life cycle of N. caninum and strategies for the control of neosporosis in cattle are discussed.read more
Citations
More filters
Journal ArticleDOI
Rabbit antibodies against Toxoplasma Hsp20 are able to reduce parasite invasion and gliding motility in Toxoplasma gondii and parasite invasion in Neospora caninum.
TL;DR: Data support a role for Hsp20 in parasite invasion and gliding motility in T. gondii and N. caninum tachyzoites with an anti-TgHsp20 serum.
Journal ArticleDOI
Mucosal immunization confers long-term protection against intragastrically established Neospora caninum infection.
Pedro Ferreirinha,Alexandra Correia,Alexandra Correia,Maria Teixeira-Coelho,Hugo Osório,Luzia Teixeira,António Rocha,Manuel Vilanova,Manuel Vilanova +8 more
TL;DR: This work shows that a previously reported mucosal immunization strategy against N. caninum infection established through the gastrointestinal tract is effective in the long term.
Journal ArticleDOI
Risk factors associated with seroprevalence of Neospora caninum in dogs from urban and rural areas of milk and coffee production in Minas Gerais state, Brazil.
Clayton I. Nogueira,Leonardo Pereira Mesquita,Camila C. Abreu,Karen Yumi Ribeiro Nakagaki,Josilene N. Seixas,Pedro S. Bezerra,Christiane Maria Barcellos Magalhães da Rocha,Antônio Marcos Guimarães,Ana Paula Peconick,Mary Suzan Varaschin +9 more
TL;DR: Investigating the risk factors related to seroprevalence in dogs from urban and rural areas with distinct economic activities in Minas Gerais state found dogs aged >4 years, dogs used as guard dogs, dogs that spontaneously hunt, and history of bovine abortion were found to be greater risk factors for canine N. caninum infection.
Journal ArticleDOI
14-3-3 Protein of Neospora caninum Modulates Host Cell Innate Immunity Through the Activation of MAPK and NF-κB Pathways.
Shan Li,Pengtao Gong,Nan Zhang,Xin Li,Lixin Tai,Xu Wang,Zhengtao Yang,Ju Yang,Xing-Quan Zhu,Xichen Zhang,Jianhua Li +10 more
TL;DR: The results indicated that the N. caninum 14-3-3 protein can induce effective immune responses and stimulate cytokine expression by activating the MAPK, AKT, and NF-κB signaling pathways but did not dependent TLR2, suggesting that Nc14- 3-3 is a novel vaccine candidate against neosporosis.
Journal ArticleDOI
Genetic characterisation of Neospora caninum strains from clinical samples of zebuine foetuses obtained in abattoirs in Goiás, Brazil.
Paula Rogério Fernandes Brom,Javier Regidor-Cerrillo,Esther Collantes-Fernández,Luis Miguel Ortega-Mora,Marcelo Sales Guimarães,Andréa Caetano da Silva +5 more
TL;DR: The first results that have been obtained regarding the molecular characterisation of strains of N. caninum from infected zebuine foetuses in South America are obtained and reveal for the first time that there are genotypic differences in the strains that are responsible for foetal transmission inZebuine Foetuses.
References
More filters
Journal ArticleDOI
Dogs are definitive hosts of Neospora caninum.
Milton M. McAllister,Jitender P. Dubey,David S. Lindsay,Jolley Wr,Rebecca A Wills,McGuire Am +5 more
TL;DR: Dogs are a definitive host of Neospora caninum, and mice inoculated with canine faecal extracts were monitored for evidence of neosporosis using a variety of morphologic, immunohistologic, serologic, and genetic analyses.
Journal ArticleDOI
A review of Neospora caninum and neosporosis
TL;DR: Neospora caninum is a recently recognized protozoan parasite of animals, which until 1988 was misidentified as Toxoplasma gondii, and its life cycle is unknown.
Journal Article
Newly recognized fatal protozoan disease of dogs
TL;DR: A newly identified parasite, Neospora caninum, structurally distinct from T gondii, was found in 10 dogs and formed meronts in many tissues of the dogs, especially the brain and spinal cord.
Journal ArticleDOI
Review of Neospora caninum and neosporosis in animals.
TL;DR: Information on biology, diagnosis, epidemiology and control of neosporosis in animals, a major cause of abortion in cattle in many countries, is reviewed.
Journal Article
Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission.
TL;DR: Neospora caninum infection was diagnosed in 5 young dogs from 2 litters with a common parentage that developed hind limb paresis 5 to 8 weeks after birth and was isolated in cell cultures, mice, and dogs inoculated with infected canine tissues.