Epidemiology and Control of Neosporosis and Neospora caninum
TLDR
This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated.Abstract:
Neospora caninum is a protozoan parasite of animals. Until 1988, it was misidentified as Toxoplasma gondii. Since its first recognition in dogs in 1984 and the description of the new genus and species Neospora caninum in 1988, neosporosis has emerged as a serious disease of cattle and dogs worldwide. Abortions and neonatal mortality are a major problem in livestock operations, and neosporosis is a major cause of abortion in cattle. Although antibodies to N. caninum have been reported, the parasite has not been detected in human tissues. Thus, the zoonotic potential is uncertain. This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated. The role of wildlife in the life cycle of N. caninum and strategies for the control of neosporosis in cattle are discussed.read more
Citations
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Genetic manipulation of Neospora caninum to express the bradyzoite-specific protein NcSAG4 in tachyzoites.
Virginia Marugán-Hernández,Luis Miguel Ortega-Mora,Adriana Aguado-Martínez,Gema Álvarez-García +3 more
TL;DR: The apparent reduction in persistence and the high growth rate of the transgenic strains, together with their constitutive expression of the protein NcSAG4, may be useful features for future immunoprophylaxis trials based on a safe live attenuated vaccine.
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Association of antibodies against Neospora caninum in mares with reproductive problems and presence of seropositive dogs as a risk factor.
Renata Azevedo de Abreu,Romildo Romualdo Weiss,Vanete Thomaz-Soccol,Rosangela Locatelli-Dittrich,Luciane Maria Laskoski,Melina Andrea Formighieri Bertol,Marilia de Oliveira Koch,Silvana Maria Alban,K.T. Green +8 more
TL;DR: The presence of seropositive dogs as a risk factor for N. caninum in mares suggests the necessity for further investigation of the epidemiology of this parasite in horse-breeding farms with reproductive problems and the presence of cattle and dogs.
Journal ArticleDOI
Development of two murine antibodies against Neospora caninum using phage display technology and application on the detection of N. caninum.
TL;DR: Two novel monoclonal antibodies, A10 and H3, were developed and demonstrated to have a potential for monitoring the N. caninum parasites in a dairy farm, which may lead to protect livestock from parasite-infection.
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Neospora caninum antibodies in dairy cows and domestic dogs from Vojvodina, Serbia
Ljiljana Kuruca,Ljubica Spasojevic-Kosic,Stanislav Simin,Milan Savović,Saša Lauš,Vesna Lalošević +5 more
TL;DR: The occurrence of N. caninum antibodies in dairy cattle and dogs in Vojvodina and possible risk factors are determined and epidemiological importance is discussed.
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The Sero-epidemiology of Neospora caninum in Cattle in Northern Tanzania.
George Semango,Clare M. Hamilton,Katharina Kreppel,Frank Katzer,Tito Kibona,Felix Lankester,Kathryn J. Allan,Kate M. Thomas,John R. Claxton,E.A. Innes,Emmanuel S. Swai,Joram Buza,Sarah Cleaveland,William A. de Glanville +13 more
TL;DR: The findings suggest N. caninum is likely to be an important cause of abortion in cattle in Tanzania and management practices, such as restricted grazing, are likely to reduce the risk of infection and suggest contamination of communal grazing areas may be important for transmission.
References
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Dogs are definitive hosts of Neospora caninum.
Milton M. McAllister,Jitender P. Dubey,David S. Lindsay,Jolley Wr,Rebecca A Wills,McGuire Am +5 more
TL;DR: Dogs are a definitive host of Neospora caninum, and mice inoculated with canine faecal extracts were monitored for evidence of neosporosis using a variety of morphologic, immunohistologic, serologic, and genetic analyses.
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A review of Neospora caninum and neosporosis
TL;DR: Neospora caninum is a recently recognized protozoan parasite of animals, which until 1988 was misidentified as Toxoplasma gondii, and its life cycle is unknown.
Journal Article
Newly recognized fatal protozoan disease of dogs
TL;DR: A newly identified parasite, Neospora caninum, structurally distinct from T gondii, was found in 10 dogs and formed meronts in many tissues of the dogs, especially the brain and spinal cord.
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Review of Neospora caninum and neosporosis in animals.
TL;DR: Information on biology, diagnosis, epidemiology and control of neosporosis in animals, a major cause of abortion in cattle in many countries, is reviewed.
Journal Article
Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission.
TL;DR: Neospora caninum infection was diagnosed in 5 young dogs from 2 litters with a common parentage that developed hind limb paresis 5 to 8 weeks after birth and was isolated in cell cultures, mice, and dogs inoculated with infected canine tissues.