Epidemiology, diagnosis, vaccines, and bibliometric analysis of the 100 top-cited studies on Hepatitis E virus
Tauseef Ahmad,Saima Nasir,Taha Hussein Musa,Saif Aldeen AlRyalat,Muhammad Hassan Khan,Jin Hui +5 more
TLDR
The information presented would be very useful in decision making for policy makers providing health care, and for academicians in providing a reference point for future research.Abstract:
In low-income countries, Hepatitis E infection is a common cause of acute hepatitis. So far, only two recombinant vaccines (rHEV and HEV 239) have been developed against Hepatitis E virus (HEV). Of...read more
Citations
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COVID-19: Zoonotic aspects.
Tauseef Ahmad,Muhammad Hassan Khan,Haroon,Taha Hussein Musa,Saima Nasir,Jin Hui,D. Katterine Bonilla-Aldana,Alfonso J. Rodriguez-Morales +7 more
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Trends in hepatitis A research indexed in the Web of Science: a bibliometric analysis over the period from 1985 to 2019.
TL;DR: A bibliometric analysis was conducted to build an all-inclusive view of the status of research on hepatitis A virus (HAV) for facilitating researchers, health professionals, and policymakers to und... as mentioned in this paper.
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Sociocultural, behavioural and political factors shaping the COVID-19 pandemic: the need for a biocultural approach to understanding pandemics and (re)emerging pathogens.
TL;DR: It is argued that a biocultural perspective on infectious disease pandemics will allow for critical reflection on how culture shapes the authors' behaviours at all levels, and how the effects of these behaviours are ultimately foundational to pathogen ecology and evolution.
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Immune dysfunction in uremia
TL;DR: It is shown that free immunoglobulin light chains per se are able to interfere with essential PMNL functions, and p-cresol was identified as a uremic solute that impairs the respiratory burst activity of PMNL.
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Global research trends in MERS-CoV: A comprehensive bibliometric analysis from 2012 to 2021
TL;DR: An insight is provided into MERS-CoV-related research for scientific community (researchers, academicians) to understand and expand the basic knowledge structure, potential collaborations, and research trend topics.
References
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Hepatitis E virus (HEV): molecular cloning and sequencing of the full-length viral genome.
Albert W. Tam,Matthew M. Smith,Martha E. Guerra,Chiao Chain Huang,Daniel W. Bradley,Kirk E. Fry,Gregory R. Reyes +6 more
TL;DR: Findings on the genetic organization and expression strategy of HEV suggest that it is the prototype human pathogen for a new class of RNA virus or perhaps a separate genus within the Caliciviridae family.
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Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route.
M. S. Balayan,A.G. Andjaparidze,S.S. Savinskaya,E.S Ketiladze,D.M. Braginsky,A.P. Savinov,V.F. Poleschuk +6 more
TL;DR: Intravenous inoculation of cynomolgus monkeys with the virus-containing stool extract resulted in histopathologically and enzymatically confirmed hepatitis, excretion of virus-like particles, and antibody response to them.
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Study of an epidemic of non-A, non-B, hepatitis. Possibility of another human hepatitis virus distinct from post-transfusion non-A, non-B type.
TL;DR: The data strongly suggest the possibility of another human hepatitis virus and established the fecal oral route of its spread.
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Hepatitis E: an emerging infection in developed countries
TL;DR: Patients with unexplained hepatitis should be tested for hepatitis E, whatever their age or travel history, and the source and route of infection remain uncertain, but it might be a porcine zoonosis.
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Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial
Fengcai Zhu,Jun Zhang,Xuefeng Zhang,Cheng Zhou,Zhong-Ze Wang,Shoujie Huang,Hua Wang,Chang-Lin Yang,Han-Min Jiang,Jia-Ping Cai,Yi-Jun Wang,Xing Ai,Yuemei Hu,Quan Tang,Xin Yao,Qiang Yan,Yangling Xian,Ting Wu,Yimin Li,Ji Miao,Mun-Hon Ng,James Wai-Kuo Shih,Ningshao Xia +22 more
TL;DR: HEV 239 is well tolerated and effective in the prevention of hepatitis E in the general population in China, including both men and women age 16-65 years and no vaccination-related serious adverse event was noted.