Erratum: Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption (Cell (2021) 184(5) (1330–1347.e13), (S0092867421001525), (10.1016/j.cell.2021.02.002))
Michelle M. McDonald,Weng Hua Khoo,Pei Ying Ng,Ya Xiao,Jad Zamerli,Peter Thatcher,Wunna Kyaw,Karrnan Pathmanandavel,Abigail K. Grootveld,Imogen Moran,Danyal Butt,Akira Nguyen,Alexander Corr,Sean C. Warren,Maté Biro,Natalie C. Butterfield,Siobhan E. Guilfoyle,Davide Komla-Ebri,Michael R.G. Dack,Hannah F. Dewhurst,John G. Logan,Yongxiao Li,Sindhu T. Mohanty,Niall M. Byrne,Rachael L. Terry,Marija K. Simic,Ryan C. Chai,Julian M.W. Quinn,Scott E. Youlten,Jessica A. Pettitt,David Abi-Hanna,Rohit Jain,Wolfgang Weninger,Mischa Lundberg,Shuting Sun,Frank H. Ebetino,Paul Timpson,Woei Ming Lee,Paul A. Baldock,Michael J. Rogers,Robert Brink,Graham R. Williams,J. H. Duncan Bassett,John P. Kemp,Nathan J. Pavlos,Peter I. Croucher,Tri Giang Phan +46 more
TLDR
The authors corrected an author oversight in the originally published version of this article, and the author contributions have been updated accordingly to reflect Alexander Corr's contributions to the scRNA-seq analysis.About:
This article is published in Cell.The article was published on 2021-04-01 and is currently open access. It has received 38 citations till now. The article focuses on the topics: Bone resorption & RANKL.read more
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Regulation and Role of Transcription Factors in Osteogenesis.
TL;DR: In this paper, a review of lineage tracing, cell sorting, and single-cell transcriptome studies has been conducted to understand the transcriptional controls in osteogenesis, including the involvement of co-factors, microRNAs, epigenetics, systemic factors, circadian rhythm, and the microenvironments.
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The Relationship Between Bone and Reproductive Hormones Beyond Estrogens and Androgens.
Edouard Mills,Lisa Yang,Morten Frost Munk Nielsen,Moustapha Kassem,Moustapha Kassem,Waljit S. Dhillo,Waljit S. Dhillo,Alexander N Comninos,Alexander N Comninos +8 more
TL;DR: A contemporary summary of the literature examining the relationship between bone biology and reproductive signals that extend beyond estrogens and androgens is provided, and include kisspeptin, gonadotropin releasing hormone, follicle stimulating hormone, luteinizing hormone, prolactin, progesterone, inhibin, activin and relaxin.
Journal ArticleDOI
Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways
Huaqiang Tao,Wenming Li,Wei Zhang,Chen Yang,Chun Zhang,Xiaolong Liang,Juan Yin,Jiaxiang Bai,Gaoran Ge,Haifeng Zhang,Xing Yang,Hongxia Li,Yaozeng Xu,Yuefeng Hao,Yu Liu,Dechun Geng +15 more
TL;DR: In this article, the effect of urolithin A (UA) administration on osteoporosis progression in the context of estrogen deficiency-induced bone loss was investigated, and in vivo results indicated that UA effectively reduced ovariectomy-induced systemic bone loss.
Journal ArticleDOI
New Insights Into Osteoclast Biology.
TL;DR: A review of osteoclast cell lineage tracing, single cell RNA sequencing, parabiosis, and intravital imaging approaches has been presented in this paper, highlighting that under homeostatic conditions very few incidences of osteocyte apoptosis occur.
Journal ArticleDOI
Shaping the bone through iron and iron-related proteins.
Maria G. Ledesma-Colunga,Heike Weidner,Maja Vujic Spasic,Lorenz C. Hofbauer,Ulrike Baschant,Martina Rauner +5 more
TL;DR: A recent review as discussed by the authors summarizes the current knowledge on the effects of iron on bone homeostasis and bone cell activities, and on the role of proteins that regulate iron homeostosis, i.e. hemochromatosis proteins and proteins of the bone morphogenetic protein pathway, on bone remodeling.
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Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
Michelle M. McDonald,Michelle M. McDonald,Weng Hua Khoo,Weng Hua Khoo,Pei Ying Ng,Ya Xiao,Jad Zamerli,Peter Thatcher,Wunna Kyaw,Karrnan Pathmanandavel,Abigail K. Grootveld,Imogen Moran,Danyal Butt,Akira Nguyen,Alexander P. Corr,Alexander P. Corr,Sean C. Warren,Maté Biro,Natalie C. Butterfield,Siobhan E. Guilfoyle,Davide Komla-Ebri,Michael R.G. Dack,Hannah F. Dewhurst,John G. Logan,Yongxiao Li,Sindhu T. Mohanty,Sindhu T. Mohanty,Niall M. Byrne,Niall M. Byrne,Rachael L. Terry,Rachael L. Terry,Marija K. Simic,Marija K. Simic,Ryan C. Chai,Julian M.W. Quinn,Julian M.W. Quinn,Scott E. Youlten,Jessica A. Pettitt,David Abi-Hanna,David Abi-Hanna,Rohit Jain,Rohit Jain,Wolfgang Weninger,Wolfgang Weninger,Wolfgang Weninger,Mischa Lundberg,Mischa Lundberg,Shuting Sun,F H Ebetino,Paul Timpson,Woei Ming Lee,Paul A. Baldock,Paul A. Baldock,Michael J. Rogers,Michael J. Rogers,Robert Brink,Robert Brink,Graham R. Williams,J. H. Duncan Bassett,John P. Kemp,John P. Kemp,Nathan J. Pavlos,Peter I. Croucher,Peter I. Croucher,Tri Giang Phan,Tri Giang Phan +65 more