Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM)
Juan Jesus Carrero,Peter Stenvinkel,Lilian Cuppari,T. Alp Ikizler,Kamyar Kalantar-Zadeh,George A. Kaysen,William E. Mitch,S. Russ Price,S. Russ Price,Christoph Wanner,Angela Yee-Moon Wang,Pieter ter Wee,Harold A. Franch,Harold A. Franch +13 more
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TLDR
This consensus statement of current knowledge on the etiology of PEW syndrome in CKD is provided to increase awareness, identify research needs, and provide the basis for future work to understand therapies and consequences of Pew.About:
This article is published in Journal of Renal Nutrition.The article was published on 2013-03-01 and is currently open access. It has received 628 citations till now. The article focuses on the topics: Wasting & Kidney disease.read more
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Toward an individualized determination of dialysis adequacy: a narrative review with special emphasis on incremental hemodialysis
Massimo Torreggiani,Antioco Fois,Linda Njandjo,Elisa Longhitano,Antoine Chatrenet,Ciro Esposito,H. Fessi,Giorgina Barbara Piccoli +7 more
TL;DR: A review of the advantages and limitations of the approaches mentioned above, focusing on the open questions regarding personalized schedules and incremental hemodialysis is presented in this paper, where the authors summarize some of the relevant issues regarding the determination of dialysis adequacy, attempting to adapt them to an elderly, highly comorbidity population.
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Prognostic Value of the Malnutrition-inflammation Score in Hospitalization and Mortality on Long-term Hemodialysis
TL;DR: In this paper , the authors assess the strength of MIS association with hospitalization and mortality in a nationwide cohort and identify a new cutoff point regarding the risk of death, MIS ≥ 6, for this study data set.
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A Joint Evaluation of Impaired Cardiac Sympathetic Responses and Malnutrition-Inflammation Cachexia for Mortality Risks in Hemodialysis Patients.
TL;DR: Considering the extremely high prevalence of cardiac autonomic neuropathy and malnutrition-inflammation cachexia in HD population, a non-invasive monitoring system composed of CSR analyzer and MIS score calculator should be developed in the artificial intelligence-based prediction of clinical events.
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Utility of the Global Leadership Initiative on Malnutrition criteria for the nutritional assessment of patients with end-stage renal disease receiving chronic hemodialysis.
TL;DR: Malnutrition assessed using the GLIM criteria could be a useful predictor of mortality and infection in patients on chronic hemodialysis and approaches for decreasing inflammation and increasing protein intake are needed.
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Peanuts or Pretzels? Changing Attitudes about Eating on Hemodialysis.
TL;DR: I am not that fond of peanuts, and I hate pretzels, but when stuck on an airplane flight, I smile when the flight attendant offers them and my pleasure is less in the food itself and more in the small ritual of hospitality that is offered.
References
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TL;DR: The prominent clinical feature of cachexia is weight loss in adults (corrected for fluid retention) or growth failure in children (excluding endocrine disorders).
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A proposed nomenclature and diagnostic criteria for protein–energy wasting in acute and chronic kidney disease
Denis Fouque,Kamyar Kalantar-Zadeh,Joel D. Kopple,Noël Cano,Philippe Chauveau,Lilian Cuppari,Harold A. Franch,Gabriele Guarnieri,Talat Alp Ikizler,George A. Kaysen,Bengt Lindholm,Ziad A. Massy,William E. Mitch,E. Pineda,Peter Stenvinkel,A. Trevinho-Becerra,Christoph Wanner +16 more
TL;DR: An expert panel to review and develop standard terminologies and definitions related to wasting, cachexia, malnutrition, and inflammation in CKD and AKI recommends the term 'protein-energy wasting' for loss of body protein mass and fuel reserves.
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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Stewart H. Lecker,R. Thomas Jagoe,Alexander Gilbert,Marcelo Gomes,Vickie E. Baracos,James L. Bailey,S. Russ Price,William E. Mitch,Alfred L. Goldberg +8 more
TL;DR: Different types of skeletal muscle atrophy share a common transcriptional program that is activated in many systemic diseases including diabetes, cancer, and renal failure, according to cDNA microarrays.
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Cytokines and major depression.
TL;DR: Although the central effects of proinflammatory cytokines appear to be able to account for most of the symptoms occurring in depression, it remains to be established whether cytokines play a causal role in depressive illness or represent epiphenomena without major significance.