Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM)
Juan Jesus Carrero,Peter Stenvinkel,Lilian Cuppari,T. Alp Ikizler,Kamyar Kalantar-Zadeh,George A. Kaysen,William E. Mitch,S. Russ Price,S. Russ Price,Christoph Wanner,Angela Yee-Moon Wang,Pieter ter Wee,Harold A. Franch,Harold A. Franch +13 more
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TLDR
This consensus statement of current knowledge on the etiology of PEW syndrome in CKD is provided to increase awareness, identify research needs, and provide the basis for future work to understand therapies and consequences of Pew.About:
This article is published in Journal of Renal Nutrition.The article was published on 2013-03-01 and is currently open access. It has received 628 citations till now. The article focuses on the topics: Wasting & Kidney disease.read more
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A Comparative Analysis of Nutritional Assessment Using Global Leadership Initiative on Malnutrition Versus Subjective Global Assessment and Malnutrition Inflammation Score in Maintenance Hemodialysis Patients
TL;DR: In this paper , the authors evaluated the performance of the recently developed GLIM (Global Leadership Initiative on Malnutrition) in MHD by assessing the agreement, accuracy, sensitivity, specificity, and survival prediction of GLIM when compared to 7-point subjective global assessment (7p-SGA) and malnutrition inflammation score (MIS).
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Combined Contribution of Reduced Functional Mobility, Muscle Weakness, and Low Serum Albumin in Prediction of All-Cause Mortality in Hemodialysis Patients: A Retrospective Cohort Study
Takahiro Shimoda,Ryota Matsuzawa,Kei Yoneki,Manae Harada,Takaaki Watanabe,Atsushi Yoshida,Yasuo Takeuchi,Atsuhiko Matsunaga +7 more
TL;DR: The results presented here indicated that the combination of reduced functional mobility, muscle weakness, and low serum albumin is useful for accurate prediction of prognosis in hemodialysis patients.
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Effect of administration of high-protein diet in rats submitted to resistance training
Thiago da Rosa Lima,Eudes Thiago Pereira Avila,Géssica Alves Fraga,Mariana de Souza Sena,Arlyson Batista de Souza Dias,Paula Caroline de Almeida,Joice Cristina dos Santos Trombeta,Roberto Carlos Vieira Junior,Amílcar Sabino Damazo,James W. Navalta,Jonato Prestes,Fabrício Azevedo Voltarelli +11 more
TL;DR: A high-protein diet promoted negative metabolic and morphological changes, while RT was effective in reversing these deleterious effects.
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Malnutrition and Sarcopenia Combined Increases the Risk for Mortality in Older Adults on Hemodialysis
Catarina Macedo,Teresa Amaral,Juliana Rodrigues,Fernanda Santin,Carla Maria Avesani,Carla Maria Avesani +5 more
TL;DR: In this article, the role of sarcopenia and malnutrition combined on the nutritional markers, quality of life, and survival in a cohort of older adults on chronic hemodialysis was evaluated.
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Geriatric nutritional risk index is associated with mortality in peritoneal dialysis patients.
TL;DR: The Geriatric Nutritional Risk Index (GNRI) is rarely used in dialysis patients, especially peritoneal dialysis (PD), and is likely to underestimate the risk of malnutrition in older patients.
References
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William J. Evans,John E. Morley,Josep M. Argilés,Connie W. Bales,Vickie E. Baracos,Denis Guttridge,Aminah Jatoi,Kamyar Kalantar-Zadeh,H. Lochs,Giovanni Mantovani,Daniel L. Marks,William E. Mitch,Maurizio Muscaritoli,Armine Najand,Piotr Ponikowski,Filippo Rossi Fanelli,Morrie Schambelan,Annemie M. W. J. Schols,Michael W. Schuster,David R. Thomas,Robert R. Wolfe,Stefan D. Anker +21 more
TL;DR: The prominent clinical feature of cachexia is weight loss in adults (corrected for fluid retention) or growth failure in children (excluding endocrine disorders).
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A proposed nomenclature and diagnostic criteria for protein–energy wasting in acute and chronic kidney disease
Denis Fouque,Kamyar Kalantar-Zadeh,Joel D. Kopple,Noël Cano,Philippe Chauveau,Lilian Cuppari,Harold A. Franch,Gabriele Guarnieri,Talat Alp Ikizler,George A. Kaysen,Bengt Lindholm,Ziad A. Massy,William E. Mitch,E. Pineda,Peter Stenvinkel,A. Trevinho-Becerra,Christoph Wanner +16 more
TL;DR: An expert panel to review and develop standard terminologies and definitions related to wasting, cachexia, malnutrition, and inflammation in CKD and AKI recommends the term 'protein-energy wasting' for loss of body protein mass and fuel reserves.
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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Stewart H. Lecker,R. Thomas Jagoe,Alexander Gilbert,Marcelo Gomes,Vickie E. Baracos,James L. Bailey,S. Russ Price,William E. Mitch,Alfred L. Goldberg +8 more
TL;DR: Different types of skeletal muscle atrophy share a common transcriptional program that is activated in many systemic diseases including diabetes, cancer, and renal failure, according to cDNA microarrays.
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Cytokines and major depression.
TL;DR: Although the central effects of proinflammatory cytokines appear to be able to account for most of the symptoms occurring in depression, it remains to be established whether cytokines play a causal role in depressive illness or represent epiphenomena without major significance.