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Open AccessJournal ArticleDOI

Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM)

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TLDR
This consensus statement of current knowledge on the etiology of PEW syndrome in CKD is provided to increase awareness, identify research needs, and provide the basis for future work to understand therapies and consequences of Pew.
About
This article is published in Journal of Renal Nutrition.The article was published on 2013-03-01 and is currently open access. It has received 628 citations till now. The article focuses on the topics: Wasting & Kidney disease.

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Journal ArticleDOI

Dietary and fluid restrictions in CKD: a thematic synthesis of patient views from qualitative studies.

TL;DR: In this paper, the authors summarize patients' perspectives of dietary and fluid management in chronic kidney disease to inform clinical practice and research, and suggest strategies to help patients adjust to dietary regimens in order to reduce their impact on quality of life.
Book ChapterDOI

Sex Differences in Muscle Wasting

TL;DR: The similarities and differences between men and women with common wasting conditions including sarcopenia and cachexia due to cancer, end-stage renal disease/chronic kidney disease, liver disease, chronic heart failure, and chronic obstructive pulmonary disease are reviewed.
Journal ArticleDOI

A Practical Approach to Nutrition, Protein-Energy Wasting, Sarcopenia, and Cachexia in Patients with Chronic Kidney Disease.

TL;DR: PEW prevention is an integral part of renal nutrition and is of paramount importance given the obesity paradox, and integrated approaches by physicians and dieticians are needed to take a holistic view of a patient’s diet beyond just control of particular laboratory parameters.
Journal ArticleDOI

The Associations of Plant Protein Intake With All-Cause Mortality in CKD

TL;DR: A diet with a higher proportion of protein from plant sources is associated with lower mortality in those with eGFR<60mL/min/1.73m(2), and future studies are warranted to determine the causal role of plant protein intake in reducing mortality.
Journal ArticleDOI

Intestinal Microbiota in Type 2 Diabetes and Chronic Kidney Disease

TL;DR: Dysbiosis is associated with endotoxemia and chronic inflammation, with disruption of the intestinal barrier and depletion of beneficial bacteria producing SCFAs, which share similar negative effects on both intestinal microbiota and function.
References
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Journal ArticleDOI

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

TL;DR: Different types of skeletal muscle atrophy share a common transcriptional program that is activated in many systemic diseases including diabetes, cancer, and renal failure, according to cDNA microarrays.
Journal ArticleDOI

Cytokines and major depression.

TL;DR: Although the central effects of proinflammatory cytokines appear to be able to account for most of the symptoms occurring in depression, it remains to be established whether cytokines play a causal role in depressive illness or represent epiphenomena without major significance.
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