Journal ArticleDOI
Fabrication of Magnetic Core@Shell Fe Oxide@Au Nanoparticles for Interfacial Bioactivity and Bio-separation
Hye-Young Park,Mark Schadt,Lingyan Wang,I-Im S. Lim,Peter N. Njoki,Soohong Kim,Min-Young Jang,Jin Luo,Chuan-Jian Zhong +8 more
TLDR
Findings of the fabrication and characterization of gold-coated iron oxide (Fe2O3 and Fe3O4) core@shell nanoparticles (Fe oxide@Au) toward novel functional biomaterials could form the basis for fabricating magnetic nanoparticles as biomaterialS with tunable size, magnetism, and surface binding properties.Abstract:
The immobilization of proteins on gold-coated magnetic nanoparticles and the subsequent recognition of the targeted proteins provide an effective means for the separation of proteins via application of a magnetic filed. A key challenge is the ability to fabricate such nanoparticles with the desired core-shell nanostructure. In this article, we report findings of the fabrication and characterization of gold-coated iron oxide (Fe2O3 and Fe3O4) core@shell nanoparticles (Fe oxide@Au) toward novel functional biomaterials. A hetero-interparticle coalescence strategy has been demonstrated for fabricating Fe oxide@Au nanoparticles that exhibit controllable sizes ranging from 5 to 100 nm and high monodispersity. Composition and surface analyses have proven that the resulting nanoparticles consist of the Fe2O3 core and the Au shell. The magnetically active Fe oxide core and thiolate-active Au shell were shown to be viable for exploiting the Au surface protein-binding reactivity for bioassay and the Fe oxide core magnetism for magnetic bioseparation. These findings are entirely new and could form the basis for fabricating magnetic nanoparticles as biomaterials with tunable size, magnetism, and surface binding properties.read more
Citations
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Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications.
TL;DR: Biocompatibility, Pharmaceutical and Biomedical Applications L. Harivardhan Reddy,‡ Jose ́ L. Arias, Julien Nicolas,† and Patrick Couvreur*,†.
Journal ArticleDOI
Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology.
Kim E. Sapsford,W. Russ Algar,Lorenzo Berti,Kelly Boeneman Gemmill,Brendan J. Casey,Eunkeu Oh,Michael H. Stewart,Igor L. Medintz +7 more
TL;DR: Chemistries that Facilitate Nanotechnology Kim E. Sapsford,† W. Russ Algar, Lorenzo Berti, Kelly Boeneman Gemmill,‡ Brendan J. Casey,† Eunkeu Oh, Michael H. Stewart, and Igor L. Medintz .
Journal ArticleDOI
Templated Techniques for the Synthesis and Assembly of Plasmonic Nanostructures
Journal ArticleDOI
Superparamagnetic graphene oxide–Fe3O4nanoparticles hybrid for controlled targeted drug carriers
TL;DR: In this paper, a superparamagnetic graphene oxide-Fe3O4nanoparticles hybrid was prepared via a simple and effective chemical precipitation method, which was then loaded with doxorubicin hydrochloride (DXR) and the loading capacity was as high as 1.08 mg mg−1.6 wt% by atomic absorption spectrometry.
Journal ArticleDOI
Colloidal heterostructured nanocrystals: Synthesis and growth mechanisms
Luigi Carbone,P. Davide Cozzoli +1 more
TL;DR: In this paper, a review of recent progress in the wet-chemical development of hybrid nanocrystals (HNCs) based on functional associations of semiconductors, metals and magnetic compounds is presented.
References
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Monodispersed Colloidal Spheres: Old Materials with New Applications
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Superparamagnetic nanoparticles for biomedical applications: Possibilities and limitations of a new drug delivery system
TL;DR: The characteristics and applications of SPION in the biomedical sector are introduced and discussed, and superparamagnetic nanoparticles based on a core consisting of iron oxides that can be targeted through external magnets are discussed.
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Magnetic nanoparticles for drug delivery
TL;DR: This review will focus on technical aspects of magnetic targeting as well as nanoparticle design and animal and clinical trials.