Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort
Ian N. Bruce,Aidan G. O'Keeffe,Vernon T. Farewell,John G. Hanly,Susan Manzi,Li Su,Dafna D. Gladman,Sang Cheol Bae,Jorge Sanchez-Guerrero,Juanita Romero-Diaz,Caroline Gordon,Daniel J. Wallace,Ann E. Clarke,Sasha Bernatsky,Ellen M. Ginzler,David A. Isenberg,Anisur Rahman,J. T. Merrill,Graciela S. Alarcón,Barri J. Fessler,Paul R. Fortin,Michelle Petri,Kristjan Steinsson,Mary Anne Dooley,Munther A. Khamashta,Rosalind Ramsey-Goldman,Asad Zoma,Gunnar Sturfelt,Ola Nived,Cynthia Aranow,Meggan Mackay,Manuel Ramos-Casals,Ronald F van Vollenhoven,Kenneth C. Kalunian,Guillermo Ruiz-Irastorza,S. Sam Lim,Diane L. Kamen,Christine A. Peschken,Murat Inanc,Murray B. Urowitz +39 more
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TLDR
It is found that several potentially modifiable risk factors for damage accrual are identified and an integrated strategy to address these may improve long-term outcomes.Abstract:
We studied damage accrual and factors determining development and progression of damage in an international cohort of systemic lupus erythematosus (SLE) patients.read more
Citations
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2019 update of the EULAR recommendations for the management of systemic lupus erythematosus
Antonis Fanouriakis,Myrto Kostopoulou,Alessia Alunno,Martin Aringer,Ingeborg M. Bajema,John Boletis,Ricard Cervera,Andrea Doria,Caroline Gordon,Marcello Govoni,Frédéric Houssiau,David Jayne,Marios Kouloumas,Annegret Kuhn,Janni Lisander Larsen,Kirsten Lerstrøm,Gabriella Moroni,Marta Mosca,Matthias Schneider,Josef S Smolen,Elisabet Svenungsson,Vladimir Tesar,Angela Tincani,Anne Troldborg,Ronald F van Vollenhoven,Jörg Wenzel,George Bertsias,Dimitrios T. Boumpas +27 more
TL;DR: The updated recommendations provide physicians and patients with updated consensus guidance on the management of SLE, combining evidence-base and expert-opinion, based on emerging new evidence.
Journal ArticleDOI
Systemic lupus erythematosus.
Arvind Kaul,Caroline Gordon,Mary K. Crow,Zahi Touma,Murray B. Urowitz,Ronald F van Vollenhoven,Guillermo Ruiz-Irastorza,Graham R. V. Hughes +7 more
TL;DR: The 10-year mortality has improved and toxic adverse effects of older medications such as cyclophosphamide and glucocorticoids have been partially offset by newer drugs such as mycophenolate mofetil and glucose-sparing regimes.
Journal ArticleDOI
Trial of Anifrolumab in Active Systemic Lupus Erythematosus
Eric F Morand,Richard Furie,Yoshiya Tanaka,Ian N. Bruce,Anca Askanase,Christophe Richez,Sang Cheol Bae,Philip Z Brohawn,Lilia Pineda,Anna Berglind,Raj Tummala,Tulip Trial Investigators +11 more
TL;DR: Anifrolumab, a human monoclonal antibody to type I interferon receptor subunit 1 investigated for the treatment of systemic lupus erythematosus (SLE), did not have a significant effect as discussed by the authors.
Journal ArticleDOI
A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)
Kenneth C. Kalunian,Joan T. Merrill,Romeo Maciuca,Jacqueline McBride,Michael J. Townsend,Xiaohui Wei,John C. Davis,William P Kennedy +7 more
TL;DR: In an exploratory analysis, rontalizumab treatment was associated with improvements in disease activity, reduced flares and decreased steroid use in patients with SLE with low ISM scores, and the primary and secondary end points of this trial were not met.
Journal ArticleDOI
The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults
Caroline Gordon,Caroline Gordon,Maame-Boatemaa Amissah-Arthur,M. Gayed,M. Gayed,Sue Brown,Ian N. Bruce,Ian N. Bruce,David D'Cruz,Benjamin Empson,Bridget Griffiths,David Jayne,Munther A. Khamashta,Munther A. Khamashta,Liz Lightstone,Peter Norton,Yvonne Norton,Karen Schreiber,David A. Isenberg +18 more
TL;DR: NICE has accredited the process used by the BSR to produce its guidance on the management of systemic lupus erythematosus in adults, valid for 5 years from 10 June 2013.
References
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The 1982 revised criteria for the classification of systemic lupus erythematosus
Eng M. Tan,Alan S. Cohen,James F. Fries,Alfonse T. Masi,Dennis J. McShane,Naomi F. Rothfield,Jane G. Schaller,Norman Talal,Robert Winchester +8 more
TL;DR: The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification and showed gains in sensitivity and specificity.
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Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.
TL;DR: In 1992, Piette and colleagues suggested that the ACR revised criteria be reevaluated in light of the above discoveries, and the presence and clinical associations or antiphospholipid antibodies in patients with SLE was suggested.
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Systemic lupus erythematosus disease activity index 2000.
TL;DR: SLEDAI-2K, which allows for persistent activity in rash, mucous membranes, alopecia, and proteinuria, is suitable for use in clinical trials and studies of prognosis in SLE.
Journal ArticleDOI
The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus.
Dafna D. Gladman,Ellen M. Ginzler,Charles H. Goldsmith,Paul R. Fortin,Matthew H. Liang,MB Urowitz,Paul A. Bacon,Stefano Bombardieri,John G. Hanly,Elaine M Hay,David A. Isenberg,Jones Jv,Kenneth C. Kalunian,Peter J. Maddison,Ola Nived,Michelle Petri,Martin Richter,Jorge Sanchez-Guerrero,M L Snaith,Gunnar Sturfelt,Deborah P M Symmons,Asad Zoma +21 more
TL;DR: This damage index for SLE records damage occurring in patients with SLE regardless of its cause and was demonstrated to have content, face, criterion, and discriminant validity.
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