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Genogroup I picobirnavirus in diarrhoeic foals: can the horse serve as a natural reservoir for human infection?

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TLDR
A PBV strain, PBV/Horse/India/BG-Eq-3/2010, was identified in the faeces of a 10 month old weaned female foal with diarrhoea in January 2010 from Kolkata, India and sequence comparison and phylogenetic analysis revealed close genetic relatedness to a human genogroup IPBV strain detected earlier from the same part of India.
Abstract
Picobirnaviruses (PBV) are small, non-enveloped viruses with a bisegmented double-stranded RNA genome. In this study a PBV strain, PBV/Horse/India/BG-Eq-3/2010, was identified in the faeces of a 10 month old weaned female foal with diarrhoea in January 2010 from Kolkata, India. Surprisingly, sequence comparison and phylogenetic analysis of a short stretch of the RNA dependent RNA polymerase gene revealed close genetic relatedness (> 98% nucleotide identity) to a human genogroup I PBV strain (Hu/GPBV1) detected earlier from the same part of India. Our observations together with earlier findings on genetic relatedness between human and animal PBV warrant further studies on zoonotic potential.

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Water quality indicators: bacteria, coliphages, enteric viruses

TL;DR: The potential of human pathogenic viruses as significant indicators of water quality is emerging and has been proposed as suitable indices for the effective identification of such organisms of human origin contaminating water systems.
Journal ArticleDOI

Exploring the virome of diseased horses.

TL;DR: The number of viruses found in horses is expanded, and their genomes are characterized to assist future epidemiological studies of their transmission and potential association with various equine diseases.
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Animal Picobirnavirus

TL;DR: Pereira et al. as mentioned in this paper presented a review of the veterinary and zoonotic aspects of animal Picobirnavirus infections since its discovery, focusing on the potential role of PBV as either a primary diarrhoeal agent or a potential pathogen in "immunocompetent individuals" or an "innocuous virus" in the intestine.
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Picobirnavirus infections: viral persistence and zoonotic potential

TL;DR: The public health aspects of PBV infection, especially its possible association with zoonosis is analyzed, as well as evidence has been found for genetic relatedness between human and animalPBV strains, suggesting extant crossing points in the ecology and evolution of heterologous PBV strains.
References
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Journal ArticleDOI

Detection of picobirnavirus in HIV-infected patients with diarrhea in Argentina.

TL;DR: Preliminary results about the circulation of picobirnavirus in HIV-infected patients in Córdoba, Argentina are offered, with picobIRnavirus detected in 8.8% of 57 HIV- infected patients with diarrhea, but it was detected in neither those without diarrhea (p<.018) nor in the group of subjects uninfected with HIV ( p<.022).
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Genomic characterisation of the large segment of a rabbit picobirnavirus and comparison with the atypical picobirnavirus of Cryptosporidium parvum

TL;DR: The 2362 base pair sequence of the larger of the two double stranded RNA genome segments of a rabbit strain of picobirnavirus has a major open reading frame (ORF) of 591 amino acids and two smaller ORFs of 55 and 155 amino acids, suggesting that there are at least two distinct classes of bisegmented dsRNA viruses or viral-like agents in faeces.
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Molecular characterization of full-length genomic segment 2 of a bovine picobirnavirus (PBV) strain: evidence for high genetic diversity with genogroup I PBVs.

TL;DR: In this article, the molecular characterization of a bovine genogroup I picobirnavirus strain RUBV-P detected from a 1-month-old diarrhoeic calf in eastern India was reported.
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Molecular diversity of partial-length genomic segment 2 of human picobirnavirus.

TL;DR: Evidence is provided that PBV may represent an emerging heterogeneous group of viruses and to establish the phylogenetic relationships of Argentine strains with PBV strains isolated in China and the USA.
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