Global Burden of Aflatoxin-Induced Hepatocellular Carcinoma: A Risk Assessment
Yan Liu,Felicia Wu +1 more
Reads0
Chats0
TLDR
Aflatoxin may play a causative role in 4.6–28.2% of all global HCC cases, and most cases occur in sub-Saharan Africa, Southeast Asia, and China where populations suffer from both high HBV prevalence and largely uncontrolled aflatoxin exposure in food.Abstract:
BackgroundHepatocellular carcinoma (HCC), or liver cancer, is the third leading cause of cancer deaths worldwide, with prevalence 16–32 times higher in developing countries than in developed countr...read more
Citations
More filters
Journal ArticleDOI
Burden of liver diseases in the world
TL;DR: The global prevalence of viral hepatitis remains high, while drug-induced liver injury continues to increase as a major cause of acute hepatitis.
Journal ArticleDOI
Safeguarding human health in the Anthropocene epoch: report of The Rockefeller Foundation–Lancet Commission on planetary health
Sarah Whitmee,Andy Haines,Chris Beyrer,Frederick Boltz,Anthony Capon,Braulio Ferreira de Souza Dias,Alex Ezeh,Howard Frumkin,Peng Gong,Peter Head,Richard Horton,Georgina M. Mace,Robert Marten,Robert Marten,Samuel S. Myers,Sania Nishtar,Steven A. Osofsky,Subhrendu K. Pattanayak,Montira J Pongsiri,Cristina Romanelli,Agnes Soucat,Jeanette Vega,Derek Yach +22 more
TL;DR: In this paper, the authors identify three categories of challenges that have to be addressed to maintain and enhance human health in the face of increasingly harmful environmental trends: conceptual and empathy failures (imagination challenges), such as an overreliance on gross domestic product as a measure of human progress, the failure to account for future health and environmental harms over present day gains, and the disproportionate eff ect of those harms on the poor and those in developing nations.
Journal ArticleDOI
The burden of primary liver cancer and underlying etiologies from 1990 to 2015 at the global, regional, and national level : results from the Global Burden of Disease Study 2015
Tomi Akinyemiju,Semaw Ferede Abera,Semaw Ferede Abera,Muktar Beshir Ahmed,Noore Alam,Noore Alam,Mulubirhan Assefa Alemayohu,Christine Allen,Rajaa Al-Raddadi,Nelson Alvis-Guzman,Yaw Ampem Amoako,Al Artaman,Tadesse Awoke Ayele,Aleksandra Barac,Isabela M. Benseñor,Adugnaw Berhane,Zulfiqar A Bhutta,Jacqueline Castillo-Rivas,Abdulaal A Chitheer,Jee-Young Choi,Benjamin C Cowie,Lalit Dandona,Lalit Dandona,Rakhi Dandona,Rakhi Dandona,Subhojit Dey,Daniel Dicker,Huyen Do Phuc,Donatus U. Ekwueme,Maysaa El Sayed Zaki,Florian Fischer,Thomas Fürst,Thomas Fürst,Thomas Fürst,Jamie Hancock,Simon I. Hay,Peter J. Hotez,Peter J. Hotez,Sun Ha Jee,Amir Kasaeian,Yousef Khader,Young-Ho Khang,G Anil Kumar,Michael Kutz,Heidi J. Larson,Alan D. Lopez,Alan D. Lopez,Raimundas Lunevicius,Raimundas Lunevicius,Reza Malekzadeh,Colm McAlinden,Toni Meier,Walter Mendoza,Ali H. Mokdad,Maziar Moradi-Lakeh,Gabriele Nagel,Quyen Nguyen,Grant Nguyen,Felix Akpojene Ogbo,George C Patton,David M. Pereira,Farshad Pourmalek,Mostafa Qorbani,Amir Radfar,Gholamreza Roshandel,Joshua A. Salomon,Juan Sanabria,Juan Sanabria,Benn Sartorius,Maheswar Satpathy,Maheswar Satpathy,Monika Sawhney,Sadaf G. Sepanlou,Katya Anne Shackelford,Hirbo Shore,Jiandong Sun,Desalegn Tadese Mengistu,Roman Topór-Mądry,Roman Topór-Mądry,Bach Xuan Tran,Bach Xuan Tran,Kingsley N. Ukwaja,Vasiliy Victorovich Vlassov,Stein Emil Vollset,Stein Emil Vollset,Theo Vos,Tolassa Wakayo,Elisabete Weiderpass,Elisabete Weiderpass,Andrea Werdecker,Naohiro Yonemoto,Mustafa Z. Younis,Mustafa Z. Younis,Chuanhua Yu,Zoubida Zaidi,Liguo Zhu,Christopher J L Murray,Mohsen Naghavi,Christina Fitzmaurice,Christina Fitzmaurice +99 more
TL;DR: In this article, the authors report results of the Global Burden of Disease (GBD) 2015 study on primary liver cancer incidence, mortality, and disability-adjusted life-years (DALYs) for 195 countries or territories from 1990 to 2015, and present global, regional, and national estimates on the burden of liver cancer attributable to hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and alcohol, and an “other” group that encompasses residual causes.
Journal ArticleDOI
World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010
Arie H. Havelaar,Arie H. Havelaar,Martyn D. Kirk,Paul R. Torgerson,Herman J. Gibb,Tine Hald,Robin J. Lake,Nicolas Praet,David C. Bellinger,Nilanthi de Silva,Neyla Gargouri,Niko Speybroeck,Amy Cawthorne,Colin Mathers,Claudia Stein,Frederick J. Angulo,Brecht Devleesschauwer +16 more
TL;DR: The Foodborne Disease Burden Epidemiology Reference Group (FERG) reports their first estimates of the incidence, mortality, and disease burden due to 31 foodborne hazards, finding that the global burden of FBD is comparable to those of the major infectious diseases, HIV/AIDS, malaria and tuberculosis.
References
More filters
Journal ArticleDOI
Hepatitis B virus infection [1] (multiple letters)
Book
Risk Assessment in the Federal Government: Managing the Process
TL;DR: The risk assessment/risk management knowledge representation was the capacity that it granted to the administrators of the EPA to design a joint decision-making process involving the various programmatic and functional offices of the agency and assembling the expertise and specific conceptions of uncertainty of toxicologists, economists, and policy analysts.
Journal ArticleDOI
Mycotoxins and human disease: a largely ignored global health issue
Christopher P. Wild,Yun Yun Gong +1 more
TL;DR: Despite the need for a better evidence-base on mycotoxins and human health, supported by better biomarkers of exposure and effect in epidemiological studies, the existing data are sufficient to prioritize exposure reduction in vulnerable populations.
Journal ArticleDOI
Science and decisions: advancing risk assessment.
TL;DR: The NRC report tackles a number of topics relating to improvements in the process, including the design and framing of risk assessments, uncertainty and variability characterization, selection and use of defaults, unification of cancer and noncancer dose-response assessment, cumulative risk assessment, and the need to increase EPA's capacity to address these improvements.
Related Papers (5)
Mycotoxins and human disease: a largely ignored global health issue
Christopher P. Wild,Yun Yun Gong +1 more