Global strategy for asthma management and prevention
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This article is published in Japanese Journal of Allergology.The article was published on 1996-09-30 and is currently open access. It has received 10451 citations till now. The article focuses on the topics: Global strategy & Asthma Control Questionnaire.read more
Citations
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Journal ArticleDOI
Curcumin attenuates allergic airway inflammation by regulation of CD4+CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice.
TL;DR: The results in vivo show ovalbumin-induced significantly broke Treg/Th17 balance; curcumin treatments markedly attenuated the inflammatory in asthma model by regulating Treg or Th17 balance, which support the possible use ofCurcumin as a therapeutic drug for patients with allergic asthma.
Journal ArticleDOI
Neutrophils in asthma—A review
TL;DR: The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes participating in airway remodeling.
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Eosinophil protein in airway macrophages: A novel biomarker of eosinophilic inflammation in patients with asthma
Neeta Kulkarni,Fay Hollins,Amanda Sutcliffe,Ruth Saunders,Sachil Shah,Salman Siddiqui,Sunil Gupta,Pranab Haldar,Ruth H. Green,Ian D. Pavord,Andrew J. Wardlaw,Christopher E. Brightling +11 more
TL;DR: Eosinophil proteins can be reliably measured in airway macrophages and, in combination with sputum eOSinophilia, the macrophage eos inophil protein content might further define the asthma phenotype and provide an additional tool to direct therapy.
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A comparison of objective and subjective measures of cough in asthma
Paul Marsden,Jaclyn A. Smith,Angela Kelsall,Emily Owen,Jonathan R. Naylor,Deborah Webster,Helen Sumner,Uazman Alam,Kevin McGuinness,Ashley Woodcock +9 more
TL;DR: Objective time spent coughing was also weak-moderately associated with subjective cough scores and visual analog scales, and most strongly correlated with cough-related quality of life (r = -0.54; P < .001).
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Non-eosinophilic Asthma: Current Perspectives
TL;DR: Research efforts are now focusing on elucidating the phenotypes underlying the non-type 2 asthma, and several studies are being conducted with new drugs and biologics aiming to develop effective strategies for this type of asthma.
References
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Dendritic cells and the control of immunity
TL;DR: Once a neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell biological analysis and the realization that these cells are a powerful tool for manipulating the immune system is realized.
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Standardization of Spirometry, 1994 Update. American Thoracic Society.
R. Crapo,John L. Hankinson,Charles G. Irvin,Neil R. MacIntyre,K. Z. Voter,Robert A. Wise,Brian L. Graham,C. O'Donnell,P. Paoletti,J. Roca,G. Veigi +10 more
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
Journal ArticleDOI
Hay fever, hygiene, and household size.
TL;DR: A possible explanation forHay fever trends over time is suggested, as well as a recent increase in the prevalence of asthma2 and childhood eczema.
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