Global strategy for asthma management and prevention
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This article is published in Japanese Journal of Allergology.The article was published on 1996-09-30 and is currently open access. It has received 10451 citations till now. The article focuses on the topics: Global strategy & Asthma Control Questionnaire.read more
Citations
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Omalizumab in patients with severe persistent allergic asthma in a real-life setting in Germany.
TL;DR: This post-marketing surveillance trial confirms the marked and clinically relevant effect of omalizumab on asthma symptoms and level of asthma control in the majority of patients with severe persistent allergic (IgE-mediated) asthma in a real-life situation.
Stepping down inhaled corticosteroids in asthma: randomised controlled trial.[see comment]
TL;DR: In this paper, the authors proposed a stepdown approach to the use of inhaled steroids at high doses in asthma, without compromising asthma control, and found that on average the stepdown group received 348 μg (95% confidence interval 202 μgto494 μg) of beclomethasone dipropionate less per day than the control group.
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Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma.
TL;DR: In this paper, the fixed combination of beclomethasone and formoterol in a hydrofluoroalkane modulite (Chiesi Farmaceutici, Parma, Italy) pressurised metered-dose inhaler (pMDI), with a combination of budesonide and Formoterol administered via a Turbuhaler (AstraZeneca, Lund, Sweden) dry powder inhaler(DPI), was compared to the marketed combination of BH and SOT in terms of efficacy and tolerability profile.
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The use of omalizumab in the treatment of severe allergic asthma: A clinical experience update.
TL;DR: Omalizumab has been shown to reduce asthma exacerbation and emergency visit rates, and to improve quality of life in patients with severe persistent allergic asthma, and is generally well tolerated.
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Relationship between airway responsiveness to mannitol and to methacholine and markers of airway inflammation, peak flow variability and quality of life in asthma patients
TL;DR: Background Airway hyperresponsiveness to stimuli that cause bronchial smooth muscle contraction indirectly through the release of endogenous mediators is thought to reflect airway inflammation more closely compared with AHR measured by stimuli that act directly on BSM.
References
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Dendritic cells and the control of immunity
TL;DR: Once a neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell biological analysis and the realization that these cells are a powerful tool for manipulating the immune system is realized.
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Standardization of Spirometry, 1994 Update. American Thoracic Society.
R. Crapo,John L. Hankinson,Charles G. Irvin,Neil R. MacIntyre,K. Z. Voter,Robert A. Wise,Brian L. Graham,C. O'Donnell,P. Paoletti,J. Roca,G. Veigi +10 more
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
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Hay fever, hygiene, and household size.
TL;DR: A possible explanation forHay fever trends over time is suggested, as well as a recent increase in the prevalence of asthma2 and childhood eczema.
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