Global strategy for asthma management and prevention
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This article is published in Japanese Journal of Allergology.The article was published on 1996-09-30 and is currently open access. It has received 10451 citations till now. The article focuses on the topics: Global strategy & Asthma Control Questionnaire.read more
Citations
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Journal ArticleDOI
Induced sputum to assess airway inflammation: a study of reproducibility
Antonio Spanevello,G. B. Migliori,Ala I. Sharara,L. Ballardini,P. Bridge,P. Pisati,Margherita Neri,P. W. Ind +7 more
TL;DR: Examination of sputum provides a direct method to investigate airway inflammation non‐invasively and appears to be a major factor in the pathogenesis of asthma and other airway diseases.
Journal ArticleDOI
Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico.
TL;DR: Age, sex and the most frequent comorbidities diabetes, obesity and hypertension were significantly associated to risk of death by COVID-19 (P<0.0001), and more attention to specific conditions might be considered during clinical admission.
Journal ArticleDOI
Unmet needs in asthma: Global Asthma Physician and Patient (GAPP) Survey: global adult findings
Giorgio Walter Canonica,Carlos E. Baena-Cagnani,Michael S. Blaiss,Ronald Dahl,Michael A. Kaliner,Erkka Valovirta +5 more
TL;DR: The GAPP Survey is the first global quantitative survey designed to uncover asthma attitudes and treatment practices among separate groups of physicians and patients, with the goal of identifying barriers to optimal management.
Journal ArticleDOI
Ultra long-acting beta 2-agonists in development for asthma and chronic obstructive pulmonary disease.
TL;DR: Once-daily dosing of an ultra LABA would be a significant convenience and probably a compliance-enhancing advantage leading to improved overall clinical outcomes in patients with asthma and chronic obstructive pulmonary disease.
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Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast.
Michael Klotsman,Timothy P. York,Sreekumar G. Pillai,Cristina Vargas-Irwin,Sanjay Sharma,Edwin J. C. G. van den Oord,Wayne Anderson +6 more
TL;DR: The overall mean response to montelukast may be skewed towards a response phenotype by a small subset of asthma patients, and CYSLTR2 and ALOX5 polymorphisms may predispose a minority of individuals to excessive cysteinyl-leukotriene concentrations, yielding a distinct asthma phenotype most likely to respond to leukotRIene modifier pharmacotherapy.
References
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Dendritic cells and the control of immunity
TL;DR: Once a neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell biological analysis and the realization that these cells are a powerful tool for manipulating the immune system is realized.
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Standardization of Spirometry, 1994 Update. American Thoracic Society.
R. Crapo,John L. Hankinson,Charles G. Irvin,Neil R. MacIntyre,K. Z. Voter,Robert A. Wise,Brian L. Graham,C. O'Donnell,P. Paoletti,J. Roca,G. Veigi +10 more
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
Journal ArticleDOI
Hay fever, hygiene, and household size.
TL;DR: A possible explanation forHay fever trends over time is suggested, as well as a recent increase in the prevalence of asthma2 and childhood eczema.
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