Global strategy for asthma management and prevention
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This article is published in Japanese Journal of Allergology.The article was published on 1996-09-30 and is currently open access. It has received 10451 citations till now. The article focuses on the topics: Global strategy & Asthma Control Questionnaire.read more
Citations
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Journal ArticleDOI
Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease
TL;DR: All three combined treatments led to statistically significant improvement in health status measurements, although the mean differences observed are relatively small in relation to the minimum clinically important difference.
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Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial
Fernando D. Martinez,Vernon M. Chinchilli,Wayne J. Morgan,Susan J. Boehmer,Robert F. Lemanske,David T. Mauger,Robert C. Strunk,Stanley J. Szefler,Robert S. Zeiger,Leonard B. Bacharier,Elizabeth Bade,Ronina A. Covar,Noah J. Friedman,Theresa W. Guilbert,Hengameh Heidarian-Raissy,H. William Kelly,Jonathan Malka-Rais,Michael Mellon,Christine A. Sorkness,Lynn M. Taussig +19 more
TL;DR: Inhaled corticosteroids as rescue medication with al buterol might be an effective step-down strategy for children with well controlled, mild asthma because it is more effective at reducing exacerbations than is use of rescue albuterol alone.
Journal ArticleDOI
Importance of inhaler devices in the management of airway disease
Johann Christian Virchow,Graham K. Crompton,R. W. Dal Negro,Shona Pedersen,Antoine Magnan,J. Seidenberg,Peter J. Barnes +6 more
TL;DR: Improvements in using inhalation devices more efficiently, in inhaler design for supporting patient compliance, and advances in inhalers technology to assure drug delivery to the lungs, have the potential to improve asthma and COPD management and control.
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Commonality of the IL-4/IL-13 pathway in atopic diseases
TL;DR: Dupilumab, a human monoclonal antibody that simultaneously inhibits signaling of IL-4 and IL-13, has demonstrated significant clinical efficacy in AD, asthma, and CSwNP, suggesting that there is a common underlying pathogenic pathway, and that IL- 4 and IL -13 cytokines are central to regulating the pathogenesis of these atopic diseases.
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Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples.
Katherine J. Baines,Katherine J. Baines,Jodie L. Simpson,Jodie L. Simpson,Lisa Wood,Lisa Wood,Rodney J. Scott,Peter G. Gibson,Peter G. Gibson +8 more
TL;DR: Genes in the IL-1 and TNF-α/nuclear factor-κB pathways were overexpressed and correlated with clinical parameters and neutrophilic airway inflammation.
References
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Dendritic cells and the control of immunity
TL;DR: Once a neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell biological analysis and the realization that these cells are a powerful tool for manipulating the immune system is realized.
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Standardization of Spirometry, 1994 Update. American Thoracic Society.
R. Crapo,John L. Hankinson,Charles G. Irvin,Neil R. MacIntyre,K. Z. Voter,Robert A. Wise,Brian L. Graham,C. O'Donnell,P. Paoletti,J. Roca,G. Veigi +10 more
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
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Hay fever, hygiene, and household size.
TL;DR: A possible explanation forHay fever trends over time is suggested, as well as a recent increase in the prevalence of asthma2 and childhood eczema.
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