Open AccessJournal Article
Herbs and herbal constituents active against snake bite.
Antony Gomes,Rinku Das,Sumana Sarkhel,Roshnara Mishra,Sanghamitra Mukherjee,Shamik Bhattacharya,Aparna Gomes +6 more
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TLDR
The present review has been focussed on the varied folk and traditional herbs and their antisnake venom compounds, which might be a stepping stone in establishing the future therapy against snake bite treatment and management.Abstract:
Snake bite, a major socio-medical problem of south east asian countries is still depending on the usage of antisera as the one and only source of treatment, which has its own limitations. In India, mostly in rural areas, health centres are inadequate and the snake bite victims mostly depend on traditional healers and herbal antidotes, as an alternative treatment. The present review has been focussed on the varied folk and traditional herbs and their antisnake venom compounds, which might be a stepping stone in establishing the future therapy against snake bite treatment and management.read more
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TL;DR: Oral administration of the plant extract at various dose levels was found to effectively inhibit the induction of haemorrhage and necrosis by the venom, confirming the anti snake venom activity of alcoholic extract of C. gigantea.
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In vivo immunomodulatory effects of the methanolic leaf extract of gymnema sylvestre in swiss albino mice
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Delineating residues for haemolytic activities of snake venom cardiotoxin 1 from Naja naja as probed by molecular dynamics simulations and in vitro validations
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Prehospital care practices for venomous snakebites in resource-limited settings: A narrative review
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References
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Book ChapterDOI
The Conservation of Medicinal Plants: Global Importance of Medicinal Plants
TL;DR: A large number of plants are used in traditional medical practices, and have been for more than 3000 years, such as in Chinese Traditional Medicine, Ayurvedic Medicine, Unani Medicine, etc., most of which probably exert therapeutic effects and would be proven as such if they were properly evaluated by Western standards.
Journal ArticleDOI
Plant natural products active against snake bite--the molecular approach.
TL;DR: From the evidence presented, it can be inferred that micromolecules which neutralize the action of snake venoms mechanistically replace endogenous antitoxic serum proteins with venom neutralizing capacity such as produced by some animals.
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Ethnobotanical survey of folk plants for the treatment of snakebites in Southern part of Tamilnadu, India.
TL;DR: Protective activity of plants-Aristolochia indica, Hemidesmus indicus, Gloriosa superba, Strychnos nux-vomica, Eclipta prostrata, and Andrographis paniculata against the lethal action of snake venom and need further investigation.
Journal ArticleDOI
Characterization of three edema-inducing phospholipase A2 enzymes from habu (Trimeresurus flavoviridis) venom and their interaction with the alkaloid aristolochic acid
TL;DR: Aristolochic acid, an alkaloid from the medicinal plant Aristolochia radix, interacts with these PLA2 enzymes and inhibits direct and indirect hemolytic activity, as well as edema-inducing activity, of TFV PL-X, but fails to neutralize the lethal potency of the enzyme.
Journal ArticleDOI
Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis ) root extracts
M.I. Alam,Aparna Gomes +1 more
TL;DR: The methanolic root extracts of Vitex negundo Linn.