Open AccessJournal Article
Herbs and herbal constituents active against snake bite.
Antony Gomes,Rinku Das,Sumana Sarkhel,Roshnara Mishra,Sanghamitra Mukherjee,Shamik Bhattacharya,Aparna Gomes +6 more
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TLDR
The present review has been focussed on the varied folk and traditional herbs and their antisnake venom compounds, which might be a stepping stone in establishing the future therapy against snake bite treatment and management.Abstract:
Snake bite, a major socio-medical problem of south east asian countries is still depending on the usage of antisera as the one and only source of treatment, which has its own limitations. In India, mostly in rural areas, health centres are inadequate and the snake bite victims mostly depend on traditional healers and herbal antidotes, as an alternative treatment. The present review has been focussed on the varied folk and traditional herbs and their antisnake venom compounds, which might be a stepping stone in establishing the future therapy against snake bite treatment and management.read more
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In vitro antioxidant and free radical scavenging activity of different parts of Tabebuia pallida growing in Bangladesh
TL;DR: Methanolic extract of T. pallida leaf is a potential source of natural antioxidants and serves as an effective free radical scavenger and/or inhibitor and might be a good plant-based pharmaceutical product for several diseases caused by free radicals.
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Neurotoxicity in Snakebite—The Limits of Our Knowledge
TL;DR: A uniform system of classification of the pattern of neuromuscular weakness and models for predicting type of toxicity and development of respiratory weakness are still lacking, and would greatly aid clinical decision making and future research.
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The genus Achyranthes: A review on traditional uses, phytochemistry, and pharmacological activities.
Xirui He,Xiaoxiao Wang,Jiacheng Fang,Yu Chang,Ning Ning,Hao Guo,Linhong Huang,Xiaoqiang Huang +7 more
TL;DR: This review aims to provide systematically reorganized information on distributions, botanical characteristics, ethnopharmacology, chemical constituents, qualitative and quantitative analysis, pharmacological activities, and toxicity of Achyranthes species to support their therapeutic potential.
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Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence.
Juliana Félix-Silva,Arnóbio Antônio da Silva-Júnior,Silvana Maria Zucolotto,Matheus F. Fernandes-Pedrosa +3 more
TL;DR: The present review provides an updated scenario and insights into future research aiming at validation of medicinal plants as antiophidic agents and strengthens the potentiality of ethnopharmacology as a tool for design of potent inhibitors and/or development of herbal medicines against venom toxins, especially local tissue damage.
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In vitro callus induction and plantlet regeneration of Achyranthes aspera L., a high value medicinal plant.
TL;DR: Different explants were good source of callus induction, morphology analysis as well as indirect plantlets regeneration and in vitro plantlets propagation from medicinally important plant Achyranthes aspera L.
References
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Coumestans as the main active principles of the liver drugs Eclipta alba and Wedelia calendulacea.
TL;DR: A HPLC-method is described for qualitative and quantitative analysis of the coumestans, in the extracts of ECLIPTA ALBA and also WEDELIA CALENDULACEA Less.
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Snakebites and ethnobotany in the northwest region of Colombia. Part III: neutralization of the haemorrhagic effect of Bothrops atrox venom.
Rafael Otero,Vitelbina Núñez,Jacqueline Barona,R. Fonnegra,Silvia L. Jiménez,R.G. Osorio,Mónica Saldarriaga,Álvaro Paúl Díaz +7 more
TL;DR: Thirty-one of 75 extracts of plants used by traditional healers for snakebites, had moderate or high neutralizing ability against the haemorrhagic effect of Bothrops atrox venom from Antioquia and Chocó, north-western Colombia.
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Rosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction
Fábio Kiss Ticli,Hage Li,R. S. Cambraia,Paulo Pereira,Angelo J. Magro,Marcos R.M. Fontes,Rodrigo G. Stábeli,Giglio,Suzelei C. França,Andreimar M. Soares,Suely Vilela Sampaio +10 more
TL;DR: The pure compound potentiated the ability of the commercial equine polyvalent antivenom in neutralizing lethal and myotoxic effects of the crude venom and of isolated PLA2s in experimental models.
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Curcumin-Artemisinin Combination Therapy for Malaria
Dalavaikodihalli Nanjaiah Nandakumar,Viswanathan Arun Nagaraj,P. G. Vathsala,Pundi N. Rangarajan,Govindarajan Padmanaban +4 more
TL;DR: Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture and in vivo, 3 oral doses ofCurcumin following a single injection of α,β-arteether to Plas modium berghei-infected mice are able to prevent recrudescence due to α, β-arte ether monotherapy and ensure almost 100% survival of the animals.
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Neutralization of lethal and myotoxic activities of south american rattlesnake venom by extracts and constituents of the plant eclipta prostrata (asteraceae)
Walter B. Mors,M C do Nascimento,José Paz Parente,M H da Silva,Paulo A. Melo,Guilherme Suarez-Kurtz +5 more
TL;DR: Ethanolic extracts of the aerial parts of Eclipta prostrata L. (Asteraceae) neutralized the lethal activity of the venom of South American rattlesnake when mixed in vitro before i.p. injection into adult Swiss mice.