Open AccessJournal Article
Herbs and herbal constituents active against snake bite.
Antony Gomes,Rinku Das,Sumana Sarkhel,Roshnara Mishra,Sanghamitra Mukherjee,Shamik Bhattacharya,Aparna Gomes +6 more
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TLDR
The present review has been focussed on the varied folk and traditional herbs and their antisnake venom compounds, which might be a stepping stone in establishing the future therapy against snake bite treatment and management.Abstract:
Snake bite, a major socio-medical problem of south east asian countries is still depending on the usage of antisera as the one and only source of treatment, which has its own limitations. In India, mostly in rural areas, health centres are inadequate and the snake bite victims mostly depend on traditional healers and herbal antidotes, as an alternative treatment. The present review has been focussed on the varied folk and traditional herbs and their antisnake venom compounds, which might be a stepping stone in establishing the future therapy against snake bite treatment and management.read more
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In vitro antioxidant and free radical scavenging activity of different parts of Tabebuia pallida growing in Bangladesh
TL;DR: Methanolic extract of T. pallida leaf is a potential source of natural antioxidants and serves as an effective free radical scavenger and/or inhibitor and might be a good plant-based pharmaceutical product for several diseases caused by free radicals.
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Neurotoxicity in Snakebite—The Limits of Our Knowledge
TL;DR: A uniform system of classification of the pattern of neuromuscular weakness and models for predicting type of toxicity and development of respiratory weakness are still lacking, and would greatly aid clinical decision making and future research.
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The genus Achyranthes: A review on traditional uses, phytochemistry, and pharmacological activities.
Xirui He,Xiaoxiao Wang,Jiacheng Fang,Yu Chang,Ning Ning,Hao Guo,Linhong Huang,Xiaoqiang Huang +7 more
TL;DR: This review aims to provide systematically reorganized information on distributions, botanical characteristics, ethnopharmacology, chemical constituents, qualitative and quantitative analysis, pharmacological activities, and toxicity of Achyranthes species to support their therapeutic potential.
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Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence.
Juliana Félix-Silva,Arnóbio Antônio da Silva-Júnior,Silvana Maria Zucolotto,Matheus F. Fernandes-Pedrosa +3 more
TL;DR: The present review provides an updated scenario and insights into future research aiming at validation of medicinal plants as antiophidic agents and strengthens the potentiality of ethnopharmacology as a tool for design of potent inhibitors and/or development of herbal medicines against venom toxins, especially local tissue damage.
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In vitro callus induction and plantlet regeneration of Achyranthes aspera L., a high value medicinal plant.
TL;DR: Different explants were good source of callus induction, morphology analysis as well as indirect plantlets regeneration and in vitro plantlets propagation from medicinally important plant Achyranthes aspera L.
References
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Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle.
Vitelbina Núñez,Victor Castro,Renato Murillo,Luis Alberto Ponce-Soto,Irmgard Merfort,Bruno Lomonte +5 more
TL;DR: Mass spectrometry determinations are consistent with the covalent modification of myotoxin by one molecule of 4-nerolidylcatechol, and a novel compound was isolated from both Piper species, sharing the nerolidyl skeleton, but nevertheless not being inhibitory towards the PLA(2)s studied.
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Neutralization of the edema-forming, defibrinating and coagulant effects of Bothrops asper venom by extracts of plants used by healers in Colombia.
Vitelbina Núñez,Rafael Otero,Jacqueline Barona,Mónica Saldarriaga,R.G. Osorio,R. Fonnegra,Silvia L. Jiménez,A. Díaz,Juan C Quintana +8 more
TL;DR: The neutralizing activity of 12 ethanolic extracts of plants against the edema-forming, defibrinating and coagulant effects of Bothrops asper venom in Swiss Webster mice was determined.
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The antisnake venom activities of Parkia biglobosa (Mimosaceae) stem bark extract.
Isaac Uzoma Asuzu,Alan L. Harvey +1 more
TL;DR: The ability of one traditionally used plant (Parkia biglobosa) to reduce the effects of two snake venoms (Naja nigricollis, and Echis ocellatus) in several experimental models was studied.
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In vitro snake venom detoxifying action of the leaf extract of Guiera senegalensis.
TL;DR: The extract of the leaves of Guiera senegalensis was found to detoxify (in vitro) venom from two common northern Nigerian snake species, Echis carinatus and Naja nigricollis, in separate experiments as discussed by the authors.
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Interaction of aristolochic acid with Vipera russelli phospholipase A2: its effect on enzymatic and pathological activities.
TL;DR: Aristolochic acid inhibits the edema-inducing activity of Vipera russelli phospholipase A2 as soon as it reaches the site, but does not aid in recovery and failed to inhibit other pathological activities of the enzyme.