High prevalence of headaches in patients with epilepsy
Xiang-qing Wang,Sen-yang Lang,Mianwang He,Xu Zhang,Fei Zhu,Wei Dai,Xiao-bing Shi,Min Wan,Yun-feng Ma,Ya-nan Chen,Shengyuan Yu +10 more
TLDR
The high prevalence of postictal headaches confirms the frequent triggering of a headache by a seizure, a condition in which the real triggering effect of the headache on the seizure might be difficult to prove.Abstract:
To examine the association between headaches and epilepsy. Consecutive adult epileptic patients who went to the outpatient clinic of the Epilepsy Center of PLA General Hospital between February 01, 2012, and May 10, 2013, were recruited into this study. A total of 1109 patients with epilepsy completed a questionnaire regarding headaches. Overall, 60.1% of the patients (male: 57.2%; female: 63.8%) reported headaches within the last year. The age-weighted prevalence of interictal migraine was 11.7% (male 8.9%, female 15.3%), which is higher than that reported in a large population-based study (8.5%, male 5.4%, female 11.6%) using the same screening questions. The prevalence of postictal headaches was 34.1% (males 32.7%, females 35.2%), and the presence of preictal headaches was 4.5% (males 4.3%, females 5.2%). The prevalence of headache yesterday in the general population was 4.8% (male 3.0%, female 6.6%). Thus, the prevalence of headaches, including migraine, is higher in epileptic patients in China. The high prevalence of postictal headaches confirms the frequent triggering of a headache by a seizure. A much lower frequency of preictal headaches, a condition in which the real triggering effect of the headache on the seizure might be difficult to prove.read more
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Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model
Jo Sourbron,Henning Schneider,Angela Kecskés,Yusu Liu,Ellen M. Buening,Lieven Lagae,Ilse Julia Smolders,Peter de Witte +7 more
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Headache in epilepsy: prevalence and clinical features
Greta Mainieri,Greta Mainieri,S. Cevoli,Giulia Giannini,Giulia Giannini,L. Zummo,L. Zummo,L. Zummo,Chiara Leta,Chiara Leta,M. Broli,M. Broli,Lorenzo Ferri,Lorenzo Ferri,Margherita Santucci,Margherita Santucci,Annio Posar,Annio Posar,Patrizia Avoni,Patrizia Avoni,Pietro Cortelli,Pietro Cortelli,Paolo Tinuper,Paolo Tinuper,Francesca Bisulli,Francesca Bisulli +25 more
TL;DR: Migraine was the most represented type of headache in patients with epilepsy, while patients with any inter-IH (migraine or TTH) are predisposed to manifest a post- IH after seizures.
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Pathophysiological Bases of Comorbidity in Migraine.
Claudia Altamura,Ilenia Corbelli,Marina de Tommaso,Cherubino Di Lorenzo,Giorgio Di Lorenzo,Antonio Di Renzo,Massimo Filippi,Tommaso B. Jannini,Roberta Messina,Pasquale Parisi,Vincenzo Parisi,Francesco Pierelli,Innocenzo Rainero,Umberto Raucci,Elisa Rubino,Paola Sarchielli,Linxin Li,Fabrizio Vernieri,C. Vollono,Gianluca Coppola +19 more
TL;DR: In this paper, the authors proposed a multidisciplinary approach to identify and eliminate possible risk and comorbidity factors for the treatment of migraine, which is designed to maintain brain homeostasis by regulating homeostatic needs such as normal subcortico-cortical excitability, energy balance, osmoregulation, and emotional response.
Journal ArticleDOI
Epilepsy and headaches: Further evidence of a link
TL;DR: It is suggested that headaches, particularly migraine-type headaches, were frequently experienced by patients with epilepsy, postictal headaches were more common, and the frequency of migraine attacks could be linked with seizure frequency and the type of treatment.
Journal ArticleDOI
Prodrome in epilepsy.
TL;DR: Prodromes are characterized by a broad spectrum of preictal symptoms that may be experienced for a duration of between 10min and several days, which usually persist until seizure onset, and usually persist for between 30min and 24h.
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