Elisa Rubino

TL;DR: This paper performed a two-stage genome-wide association study with 111,326 clinically diagnosed/proxy AD cases and 677,663 controls and found 75 risk loci, of which 42 were new at the time of analysis.

TL;DR: Quarantine induces a rapid increase of BPSD in approximately 60% of patients and stress-related symptoms in two-thirds of caregivers and were associated with increased patients’ neuropsychiatric burden (p<0.0001); health services need to plan a post-pandemic strategy.

TL;DR: The findings suggest that immune system processes (link to 6p21.3) and possibly lysosomal and autophagy pathways ( link to 11q14) are potentially involved in FTD.

TL;DR: Evaluated the frequency of SQSTM1 mutations in a dataset of unrelated patients with FTLD or ALS, in comparison with healthy controls and patients with Paget disease of bone (PDB), and suggested a pathogenetic role for these mutations.

TL;DR: Evidence is provided for an association of the MTHFR gene only in migraine with aura only in TT genotypes, which is associated with a higher risk of disease compared with the CC genotype.