Journal ArticleDOI
HLA-A2 as a target for cell-mediated lympholysis: evidence from immunoselected HLA-A2 negative mutant cell lines.
TLDR
Cloned mutants of the human B lymphoblastoid cell line SB have been isolated using mutagenesis with ethyl methanesulfonate followed by negative selection with an anti-HLA-A2 serum and complement to provide new line of evidence that HLA antigens recognized by antibody can also be the true molecular targets for cytotoxic T lymphocytes.About:
This article is published in Human Immunology.The article was published on 1980-07-01. It has received 131 citations till now. The article focuses on the topics: Cytotoxic T cell & Staphylococcus aureus protein A.read more
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An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein
Stefan Meuer,Rebecca E. Hussey,Marina Fabbi,David A. Fox,Oreste Acuto,K A Fitzgerald,James C. Hodgdon,Jeffrey P. Protentis,Stuart F. Schlossman,Ellis L. Reinherz +9 more
TL;DR: Given that T11 is the earliest T-lineage surface glycoprotein to appear in thymic ontogeny and is thus expressed before T3-Ti, the former may be involved in clonal expansion and/or differentiation during early development.
Journal ArticleDOI
Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.
Stefan Meuer,K A Fitzgerald,Rebecca E. Hussey,James C. Hodgdon,Stuart F. Schlossman,Ellis L. Reinherz +5 more
TL;DR: The development of monoclonal antibodies to such polymorphic T cell surface structures should provide important probes to further define the surface receptor for antigen.
Citation-classic - monoclonal-antibodies for analysis of the hla system
TL;DR: In this paper, a monoclonal antibody against determinants of the HLA-A,B,C glycoproteins and pjmicroglobulin was developed.
Journal ArticleDOI
Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.
TL;DR: The results indicate that T4+ and T8+ T lymphocytes have receptors for different classes of MHC antigens and suggest cytotoxic T 4+ subpopulations might be important in human transplantation and autoimmune disorders.
Journal ArticleDOI
Expression of myeloid differentiation antigens on normal and malignant myeloid cells.
TL;DR: A series of monoclonal antibodies have been characterized that define four surface antigens (MY3, MY4, MY7, and MY8) of human myeloid cells derived from a fusion of the NS-1 plasmacytoma cell line with splenocytes from a mouse immunized with human acute myelomonocytic leukemia cells.
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Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Journal ArticleDOI
A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels
TL;DR: A simple method for detecting 3H in polyacrylamide gels by scintillation autography (fluorography) using X-ray film, which is ten times more sensitive than conventional autoradiography of isotopes with higher emission energies.
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Monoclonal antibodies for analysis of the HLA system.
TL;DR: III Antibodies A Monoclonal antibodies against determinants of the HLA-A,B,C glycoproteins and pjmicroglobulin and pJmicroglOBulin against species specific, non-polymorphic determinants 2.