ICTV Virus Taxonomy Profile: Polyomaviridae.
Ugo Moens,Sébastien Calvignac-Spencer,Chris Lauber,Torbjörn Ramqvist,Mariet C.W. Feltkamp,Matthew D. Daugherty,Ernst J. Verschoor,Bernhard Ehlers +7 more
TLDR
The Polyomaviridae is a family of small, non-enveloped viruses with circular dsDNA genomes of approximately 5 kbp whose members have restricted host range, infecting mammals and birds.Abstract:
The Polyomaviridae is a family of small, non-enveloped viruses with circular dsDNA genomes of approximately 5 kbp. The family includes four genera whose members have restricted host range, infecting mammals and birds. Polyomavirus genomes have also been detected recently in fish. Merkel cell polyomavirus and raccoon polyomavirus are associated with cancer in their host; other members are human and veterinary pathogens. Clinical manifestations are obvious in immunocompromised patients but not in healthy individuals. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Polyomaviridae, which is available at www.ictv.global/report/polyomaviridae.read more
Citations
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Viral indicators for tracking domestic wastewater contamination in the aquatic environment.
Kata Farkas,David I. Walker,Evelien M. Adriaenssens,James E. McDonald,Luke S. Hillary,Shelagh K. Malham,Davey L. Jones +6 more
TL;DR: Viral indicators are suitable for the long-term monitoring of viral contamination in freshwater and marine environments and should be implemented within monitoring programmes to provide a holistic assessment of microbiological water quality and wastewater-based epidemiology, improve current risk management strategies and protect global human health.
Journal ArticleDOI
The interplay between viral-derived miRNAs and host immunity during infection
TL;DR: The origin and biogenesis of viral miRNAs during the viral lifecycle is highlighted and insights into the underexplored role of viralMiRNAs as potential targets for developing therapeutics for treating complex viral diseases are offered.
Journal ArticleDOI
The Diverse Roles of microRNAs at the Host⁻Virus Interface.
Annie Bernier,Selena M. Sagan +1 more
TL;DR: This review focuses on recent findings elucidating several key mechanisms employed by diverse virus families, with a focus on miRNAs at the host–virus interface during herpesvirus, polyomavirus, retroviruses, pestivirus, and hepacivirus infections.
Journal ArticleDOI
Human polyomaviruses and cancer: an overview.
José Carlos Mann Prado,T A Monezi,Aline T. Amorim,Vanesca de Souza Lino,Andressa Paladino,Enrique Boccardo +5 more
TL;DR: Present evidence only supports the role of MCPyV as a carcinogen to humans, and a summarized discussion on the current knowledge concerning the roleof MCPYV, TSPyV, JCPy V and BKPyV in human cancers is presented.
Journal ArticleDOI
Biology of the BKPyV: An Update.
François Helle,Etienne Brochot,Lynda Handala,Elodie Martin,Sandrine Castelain,Catherine François,Gilles Duverlie +6 more
TL;DR: An update on recent advances in understanding the biology of BKPyV is provided and the only therapeutic option is a modulation of the immunosuppressive drug regimen to improve immune control though it may increase the risk of rejection.
References
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Origins and evolution of viruses of eukaryotes: The ultimate modularity
TL;DR: Strikingly, evolution of all classes of eukaryotic viruses appears to have involved fusion between structural and replicative gene modules derived from different sources along with additional acquisitions of diverse genes.
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The structure of simian virus 40 refined at 3.1 A resolution.
TL;DR: It is proposed that the contact between five-coordinated and six- Coordinated pentamers may help to generate a six-pentamer nucleus, with which further pentamerers can assemble to generate the complete particle.
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A cornucopia of human polyomaviruses
TL;DR: The similarities and differences among the new human polyomaviruses are described and how these viruses might interact with their human host are discussed.
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The Ancient Evolutionary History of Polyomaviruses.
Christopher B. Buck,Koenraad Van Doorslaer,Alberto Peretti,Eileen M. Geoghegan,Michael J. Tisza,Ping An,Joshua P. Katz,James M. Pipas,Alison A. McBride,Alvin C. Camus,Alexa J. McDermott,Jennifer A. Dill,Eric Delwart,Eric Delwart,Terry Fei Fan Ng,Terry Fei Fan Ng,Kata Farkas,Charlotte Austin,Simona Kraberger,William Davison,Diana V. Pastrana,Arvind Varsani,Arvind Varsani,Arvind Varsani +23 more
TL;DR: Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years.
Journal ArticleDOI
A taxonomy update for the family Polyomaviridae.
Sébastien Calvignac-Spencer,Mariet C.W. Feltkamp,Matthew D. Daugherty,Ugo Moens,Torbjörn Ramqvist,Reimar Johne,Bernhard Ehlers +6 more
TL;DR: An updated taxonomy of the family Polyomaviridae, with new criteria for definition and creation of polyomavirus species established that were based on the observed distance between large T antigen coding sequences.