Imaging challenges in biomaterials and tissue engineering.
Alyssa A. Appel,Mark A. Anastasio,Jeffery C. Larson,Jeffery C. Larson,Eric M. Brey,Eric M. Brey +5 more
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TLDR
This review focuses on evaluating the application of available imaging modalities for assessment of biomaterials and tissue in TERM applications and a discussion of limitations of these techniques and identification of areas for further development.About:
This article is published in Biomaterials.The article was published on 2013-09-01 and is currently open access. It has received 235 citations till now.read more
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Regenerative medicine: Current therapies and future directions.
Angelo S. Mao,David J. Mooney +1 more
TL;DR: Developments in fabricating sophisticated grafts and tissue mimics and technologies for integrating grafts with host vasculature will be discussed, and directions for current and future regenerative medicine therapies are proposed.
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Sequential Drug Release and Enhanced Photothermal and Photoacoustic Effect of Hybrid Reduced Graphene Oxide-Loaded Ultrasmall Gold Nanorod Vesicles for Cancer Therapy.
Jibin Song,Xiangyu Yang,Orit Jacobson,Lisen Lin,Peng Huang,Gang Niu,Qingjie Ma,Xiaoyuan Chen +7 more
TL;DR: The rGO-AuNRVe-DOX capable of sequential DOX release by laser light and acid environment may have the potential for clinical translation to treat cancer patients with tumors accessible by light.
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Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine
Kevin Dzobo,Kevin Dzobo,Nicholas Ekow Thomford,Dimakatso Alice Senthebane,Dimakatso Alice Senthebane,Hendrina Shipanga,Hendrina Shipanga,Arielle Rowe,Collet Dandara,Michael Pillay,Keolebogile Shirley Motaung +10 more
TL;DR: Several challenges must be overcome in the application of 3D bioprinting before this disruptive technology is widely used to create organotypic constructs for regenerative medicine.
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Engineering Cellular Microenvironments with Photo- and Enzymatically Responsive Hydrogels: Toward Biomimetic 3D Cell Culture Models.
TL;DR: Progress is described in designing stimuli-responsive, optically transparent hydrogels that can be used as biomimetic extracellular matrices (ECMs) to study cell differentiation and migration in the context of modeling the nervous system and cancer.
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Imaging strategies for tissue engineering applications.
TL;DR: Commonly used biomedical imaging modalities, including X-ray and computed tomography, positron emission tomography and single photon emission computed tomographic, magnetic resonance imaging, ultrasound imaging, optical imaging, and emerging techniques and multimodal imaging, will be discussed, focusing on the latest trends of their applications in recent tissue engineering studies.
References
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Advances in Clinical and Biomedical Applications of Photoacoustic Imaging.
Jimmy L. Su,Bo Wang,Katheryne E. Wilson,Carolyn L. Bayer,Yun Sheng Chen,Seungsoo Kim,Kimberly A. Homan,Stanislav Emelianov +7 more
TL;DR: The technology is still in its infancy, much work has been done in the pre-clinical arena, and photoacoustic imaging is fast approaching the clinical setting, as well as some of the challenges that must be addressed to move photoac acoustic imaging into the clinical realm.
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Non-destructive three-dimensional evaluation of a polymer sponge by micro-tomography using synchrotron radiation
Bert Müller,Felix Beckmann,Marius Huser,Fabrice Maspero,Gábor Székely,Kurt Ruffieux,Philipp J. Thurner,Erich Wintermantel +7 more
TL;DR: X-ray micro-tomography, a non-destructive technique used to uncover the complex 3-D micro-architecture of a degradable polymer sponge designed for bone augmentation, elucidate that synchrotron radiation at the photon energy of 9 keV has an appropriate cross section for this low-weight material.
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Going beyond histology. Synchrotron micro-computed tomography as a methodology for biological tissue characterization: from tissue morphology to individual cells
Rolf Zehbe,Astrid Haibel,Heinrich Riesemeier,Ulrich Gross,Ulrich Gross,C. James Kirkpatrick,Helmut Schubert,Christoph Brochhausen +7 more
TL;DR: Three-dimensional morphological characterization of articular cartilage using synchrotron-generated X-rays demonstrating the spatial distribution of single cells inside the tissue and their quantification is reported, while comparing the findings to conventional histological techniques.
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Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering.
John V. Terrovitis,Jeff W.M. Bulte,Sajiram Sarvananthan,Lindsey A. Crowe,Padmini Sarathchandra,Puspa Batten,Eleftherios Sachlos,Adrian H. Chester,Jan T. Czernuszka,David N. Firmin,Patricia M. Taylor,Magdi H. Yacoub +11 more
TL;DR: Ferumoxide labeling of human MSCs seeded on collagen scaffolds is an effective, non-toxic technique for visualization of these cells using MRI and appears promising for cell tracking in future tissue-engineering applications.