Imaging challenges in biomaterials and tissue engineering.
Alyssa A. Appel,Mark A. Anastasio,Jeffery C. Larson,Jeffery C. Larson,Eric M. Brey,Eric M. Brey +5 more
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TLDR
This review focuses on evaluating the application of available imaging modalities for assessment of biomaterials and tissue in TERM applications and a discussion of limitations of these techniques and identification of areas for further development.About:
This article is published in Biomaterials.The article was published on 2013-09-01 and is currently open access. It has received 235 citations till now.read more
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MRI Visualization of Injectable Ureidopyrimidinone Hydrogelators by Supramolecular Contrast Agent Labeling
Maarten H. Bakker,Cheyenne C. S. Tseng,Henk M. Keizer,Peter R. Seevinck,Henk M. Janssen,Frebus J. van Slochteren,Steven A. J. Chamuleau,Patricia Y. W. Dankers +7 more
TL;DR: An injectable supramolecular ureidopyrimidinone‐based hydrogel is functionalized with a modified Gadolinium(III)‐DOTA complex (UPy‐Gd) for contrast enhanced MRI to enable high‐quality imaging of this hydrogels.
Journal ArticleDOI
Use of fluorescence lifetime imaging microscopy (FLIM) as a timer of cell cycle S phase
TL;DR: It is shown that quantitative and accurate FLIM technique allows high-content, multi-parametric dynamic analyses, far superior to the intensity-based imaging.
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NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring.
Peng Pei,Hongxing Hu,Ying Chen,Shan Teng Wang,Jiang Ming,Yiwei Yang,Cai Xia Sun,Shichang Zhao,Fan Zhang +8 more
TL;DR: An integrated second near-infrared (Nir-II, 1000-1700 nm) window in vivo imaging strategy based on 3D-printed bioactive glass scaffolds doped with NIR-II ratiometric lanthanide-dye hybrid nanoprobes, allowing for in situ monitoring of the early inflammation, angiogenesis, and implant degradation during mouse skull repair.
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In Vivo Tracking of Tissue Engineered Constructs
Carmen J. Gil,Martin L. Tomov,Andrea S. Theus,Alexander Cetnar,Morteza Mahmoudi,Vahid Serpooshan,Vahid Serpooshan +6 more
TL;DR: This article reviews the imaging techniques that are currently being adopted in both research and clinical studies to track tissue engineering scaffolds in vivo, with special attention to 3D bioprinted tissue constructs.
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Nondestructive Assessment of Engineered Cartilage Composition by Near Infrared Spectroscopy
Cushla McGoverin,Arash Hanifi,Uday Palukuru,Farzad Yousefi,Padraig Glenn,Michael Shockley,Richard G. Spencer,Nancy Pleshko +7 more
TL;DR: Results demonstrate that NIR spectroscopy combined with multivariate analysis provides a nondestructive modality to assess engineered cartilage, which could provide information to determine the optimal time for tissue harvest for clinical applications.
References
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Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs
Lihong V. Wang,Song Hu +1 more
TL;DR: A review of the state of the art of photoacoustic tomography for both biological and clinical studies can be found in this paper, where the authors discuss the current state-of-the-art and discuss future prospects.
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Optical coherence tomography for ultrahigh resolution in vivo imaging
TL;DR: Optical coherence tomography functions as a type of 'optical biopsy' to provide cross-sectional images of tissue structure on the micron scale and is a promising imaging technology because it can provide images of tissues in situ and in real time, without the need for excision and processing of specimens.
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Correction: Corrigendum: Nature of hardness evolution in nanocrystalline NiTi shape memory alloys during solid-state phase transition
Abbas Amini,Chun Cheng +1 more
TL;DR: In this paper, the authors measured the hardness of pseudoelastic NiTi shape memory alloys (SMAs) during the solid-state phase transition in NiTi SMAs.
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Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model
TL;DR: The results indicate that delivery of both growth factors may enhance bone bridging and union of the critical size defect compared to delivery of BMP-2 alone and suggests an interplay between these growth factors for early bone regeneration.
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A comparison of micro CT with other techniques used in the characterization of scaffolds.
TL;DR: Micro CT is a more recent method of examining the characteristics of scaffolds and this review aims to highlight this current approach while comparing it with other techniques.