Imaging challenges in biomaterials and tissue engineering.
Alyssa A. Appel,Mark A. Anastasio,Jeffery C. Larson,Jeffery C. Larson,Eric M. Brey,Eric M. Brey +5 more
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TLDR
This review focuses on evaluating the application of available imaging modalities for assessment of biomaterials and tissue in TERM applications and a discussion of limitations of these techniques and identification of areas for further development.About:
This article is published in Biomaterials.The article was published on 2013-09-01 and is currently open access. It has received 235 citations till now.read more
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Regenerative medicine: Current therapies and future directions.
Angelo S. Mao,David J. Mooney +1 more
TL;DR: Developments in fabricating sophisticated grafts and tissue mimics and technologies for integrating grafts with host vasculature will be discussed, and directions for current and future regenerative medicine therapies are proposed.
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Sequential Drug Release and Enhanced Photothermal and Photoacoustic Effect of Hybrid Reduced Graphene Oxide-Loaded Ultrasmall Gold Nanorod Vesicles for Cancer Therapy.
Jibin Song,Xiangyu Yang,Orit Jacobson,Lisen Lin,Peng Huang,Gang Niu,Qingjie Ma,Xiaoyuan Chen +7 more
TL;DR: The rGO-AuNRVe-DOX capable of sequential DOX release by laser light and acid environment may have the potential for clinical translation to treat cancer patients with tumors accessible by light.
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Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine
Kevin Dzobo,Kevin Dzobo,Nicholas Ekow Thomford,Dimakatso Alice Senthebane,Dimakatso Alice Senthebane,Hendrina Shipanga,Hendrina Shipanga,Arielle Rowe,Collet Dandara,Michael Pillay,Keolebogile Shirley Motaung +10 more
TL;DR: Several challenges must be overcome in the application of 3D bioprinting before this disruptive technology is widely used to create organotypic constructs for regenerative medicine.
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Engineering Cellular Microenvironments with Photo- and Enzymatically Responsive Hydrogels: Toward Biomimetic 3D Cell Culture Models.
TL;DR: Progress is described in designing stimuli-responsive, optically transparent hydrogels that can be used as biomimetic extracellular matrices (ECMs) to study cell differentiation and migration in the context of modeling the nervous system and cancer.
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Imaging strategies for tissue engineering applications.
TL;DR: Commonly used biomedical imaging modalities, including X-ray and computed tomography, positron emission tomography and single photon emission computed tomographic, magnetic resonance imaging, ultrasound imaging, optical imaging, and emerging techniques and multimodal imaging, will be discussed, focusing on the latest trends of their applications in recent tissue engineering studies.
References
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Long-term results of cell-free biodegradable scaffolds for in situ tissue-engineering vasculature: in a canine inferior vena cava model.
Goki Matsumura,Naotaka Nitta,Shojiro Matsuda,Yuki Sakamoto,Noriko Isayama,Kenji Yamazaki,Yoshito Ikada +6 more
TL;DR: It is concluded that the findings shown above provide direct evidence that the new scaffold can be useful for cell-free tissue-engineering of vasculature and would be applicable for pediatric cardiovascular surgery involving biocompatible materials.
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Nondestructive Evaluation of Hydrogel Mechanical Properties Using Ultrasound
Jason Walker,Ashley M. Myers,Mark D. Schluchter,Victor M. Goldberg,Arnold I. Caplan,Jim Berilla,Joseph M. Mansour,Jean F. Welter +7 more
TL;DR: The feasibility of using ultrasound technology as a noninvasive, nondestructive method for evaluating the mechanical properties of engineered weight-bearing tissues was evaluated and a correlation between estimates of compressive modulus from ultrasonic and mechanical measurements was found, but the correlation depended on the model used to estimate the modulus.
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Constitutive Modeling of Porcine Liver in Indentation Using 3D Ultrasound Imaging
TL;DR: This work presents constitutive model selection and parameter estimation for perfused porcine liver in indentation, and demonstrates that a quasilinear viscoelastic model with shear modulus relaxation offers good model-experiment agreement in terms of indenter displacement and tissue displacement field.
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T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation: initial results on clinical use with 3.0-Tesla MRI
Goetz H. Welsch,Goetz H. Welsch,Siegfried Trattnig,Timothy R. Hughes,S. Quirbach,Alexander Olk,M. Blanke,Stefan Marlovits,Tallal C. Mamisch,Tallal C. Mamisch +9 more
TL;DR: In this paper, the authors used T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation (MACT) of the knee, and compared and correlated both methodologies.
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Contrast-enhanced nanofocus computed tomography images the cartilage subtissue architecture in three dimensions.
TL;DR: CE-nanoCT can provide novel insights in preclinical research by quantifying in a non-destructive 3D manner pathological differences, in particular in developing mice, newborns or adults.