Imaging challenges in biomaterials and tissue engineering.
Alyssa A. Appel,Mark A. Anastasio,Jeffery C. Larson,Jeffery C. Larson,Eric M. Brey,Eric M. Brey +5 more
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TLDR
This review focuses on evaluating the application of available imaging modalities for assessment of biomaterials and tissue in TERM applications and a discussion of limitations of these techniques and identification of areas for further development.About:
This article is published in Biomaterials.The article was published on 2013-09-01 and is currently open access. It has received 235 citations till now.read more
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Vascularisation in regenerative therapeutics and surgery.
Rebecca Jeyaraj,Natasha G,Georgia Kirby,Georgia Kirby,Jayakumar Rajadas,A. Mosahebi,Alexander M. Seifalian,Aaron Tan,Aaron Tan +8 more
TL;DR: Future prospects in this field are likely to depend on the adoption of a wide-ranging approach incorporating a combination of salient themes such as genetic manipulation, modular assembly and bioreactor coupling.
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Trigger-responsive engineered-nanocarriers and image-guided theranostics for rheumatoid arthritis
Nadim Ahamad,Ameya Prabhakar,Sourabh Mehta,Sourabh Mehta,Ekta Singh,Eshant Bhatia,Shivam Sharma,Rangan Banerjee +7 more
TL;DR: Progress made in recently emerging 'trigger-responsive' and 'image-guided theranostics' ENCs for RA treatment has been explored with emphasis on the design strategies, mechanism, current status, challenges, and translational perspectives.
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In vivo photoacoustic guidance of stem cell injection and delivery for regenerative spinal cord therapies.
TL;DR: The in vivo feasibility of an intraoperative imaging approach to guide stem cell injection to the spinal cord in vivo is demonstrated, which is a critical step toward the development of a US/PA/MRI platform to monitor regenerative spinal cord therapies.
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Ultrasmall Superparamagnetic Iron Oxide Labeled Silk Fibroin/Hydroxyapatite Multifunctional Scaffold Loaded With Bone Marrow-Derived Mesenchymal Stem Cells for Bone Regeneration.
TL;DR: Wang et al. as discussed by the authors showed that the incorporation of USPIO nanoparticles into bone marrow-derived mesenchymal stem cells (BMSCs) loaded with multifunctional scaffolds promoted cell adhesion and growth, and facilitated osteogenesis by showing increased levels of alkaline phosphatase activity and up-regulation of osteoblastic genes.
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In situ process monitoring and automated multi-parameter evaluation using optical coherence tomography during extrusion-based bioprinting
TL;DR: In this article, a 3D extrusion-based bioprinter-associated optical coherence tomography (3D P-OCT) was demonstrated to achieve high-speed, wide-field and full-depth imaging, and provided in situ process monitoring and comprehensive evaluation for 3D bioprinting.
References
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Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs
Lihong V. Wang,Song Hu +1 more
TL;DR: A review of the state of the art of photoacoustic tomography for both biological and clinical studies can be found in this paper, where the authors discuss the current state-of-the-art and discuss future prospects.
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Optical coherence tomography for ultrahigh resolution in vivo imaging
TL;DR: Optical coherence tomography functions as a type of 'optical biopsy' to provide cross-sectional images of tissue structure on the micron scale and is a promising imaging technology because it can provide images of tissues in situ and in real time, without the need for excision and processing of specimens.
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Correction: Corrigendum: Nature of hardness evolution in nanocrystalline NiTi shape memory alloys during solid-state phase transition
Abbas Amini,Chun Cheng +1 more
TL;DR: In this paper, the authors measured the hardness of pseudoelastic NiTi shape memory alloys (SMAs) during the solid-state phase transition in NiTi SMAs.
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Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model
TL;DR: The results indicate that delivery of both growth factors may enhance bone bridging and union of the critical size defect compared to delivery of BMP-2 alone and suggests an interplay between these growth factors for early bone regeneration.
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A comparison of micro CT with other techniques used in the characterization of scaffolds.
TL;DR: Micro CT is a more recent method of examining the characteristics of scaffolds and this review aims to highlight this current approach while comparing it with other techniques.