Non-invasive monitoring of tissue scaffold degradation using ultrasound elasticity imaging
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TLDR
Preliminary in vitro and in vivo results with poly(1,8-octanediol-co-citrate) scaffolds support the feasibility of UEI as a non-invasive quantitative monitoring tool for scaffold degradation and engineered tissue formation.About:
This article is published in Acta Biomaterialia.The article was published on 2008-07-01 and is currently open access. It has received 119 citations till now. The article focuses on the topics: Elasticity Imaging Techniques & Scaffold.read more
Citations
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Nanodiamond Particles: Properties and Perspectives for Bioapplications
TL;DR: This review critically examines the use of NDs for biomedical applications based on type (i.e., high-pressure high-temperature [HPHT], CVD diamond, detonation ND [DND]), post-synthesis processing and modifications, and resultant properties including bio-interfacing.
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A review of tissue-engineered skin bioconstructs available for skin reconstruction
TL;DR: Those materials already commercially available for clinical use as well as to give a short insight to those under development are described to provide skin scientists/tissue engineers with the information required to move closer to achieving the ultimate goal of an off-the-shelf, complete full-thickness skin replacement.
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Imaging challenges in biomaterials and tissue engineering.
Alyssa A. Appel,Mark A. Anastasio,Jeffery C. Larson,Jeffery C. Larson,Eric M. Brey,Eric M. Brey +5 more
TL;DR: This review focuses on evaluating the application of available imaging modalities for assessment of biomaterials and tissue in TERM applications and a discussion of limitations of these techniques and identification of areas for further development.
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Hydrolytic Degradation and Erosion of Polyester Biomaterials
TL;DR: Through better control of degradation behavior and correlation of in vitro, simulated degradation to that observed in vivo, the development of superior devices prepared with polyester biomaterials may be achieved.
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Tailoring the mechanical properties of 3D-designed poly(glycerol sebacate) scaffolds for cartilage applications.
TL;DR: It is shown that the bulk modulus of poly(glycerol sebacate) (PGS) can be changed by varying molar ratios during prepolymer synthesis and by varying curing time, and that this relatively new biomedical material supports cartilaginous matrix production by chondrocytes in vitro.
References
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Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues
TL;DR: Initial results of several phantom and excised animal tissue experiments are reported which demonstrate the ability of this technique to quantitatively image strain and elastic modulus distributions with good resolution, sensitivity and with diminished speckle.
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Porous scaffold design for tissue engineering
TL;DR: The integration of CTD with SFF to build designer tissue-engineering scaffolds is reviewed and the mechanical properties and tissue regeneration achieved using designer scaffolds are details.
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Elastography of breast lesions: initial clinical results.
TL;DR: Elastography has the potential to be useful in the evaluation of areas of shadowing on the sonogram and also may be helpful in the distinction of benign from malignant masses.
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Internal displacement and strain imaging using ultrasonic speckle tracking
TL;DR: In this paper, the authors extended the ultrasound speckle tracking method to allow measurement of internal displacement and strain fields over a wide dynamic range of tissue motion, which should lead to enhanced contrast resolution in strain and elasticity images.
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Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints.
TL;DR: An image-based homogenization optimization approach is demonstrated that can design scaffold microstructure, scaffold material and regenerate tissueMicrostructure to meet conflicting design requirements and ensure adequate cell/gene delivery can be introduced using a minimum porosity threshold.