Journal ArticleDOI
MEGA2 : Molecular evolutionary genetics analysis software
TLDR
MEGA2 vastly extends the capabilities of MEGA version 1 by facilitating analyses of large datasets, enabling creation and analyses of groups of sequences, and expanding the repertoire of statistical methods for molecular evolutionary studies.Abstract:
Summary: We have developed a new software package, Molecular Evolutionary Genetics Analysis version 2 (MEGA2), for exploring and analyzing aligned DNA or protein sequences from an evolutionary perspective. MEGA2 vastly extends the capabilities of MEGA version 1 by: (1) facilitating analyses of large datasets; (2) enabling creation and analyses of groups of sequences; (3) enabling specification of domains and genes; (4) expanding the repertoire of statistical methods for molecular evolutionary studies; and (5) adding new modules for visual representation of input data and output results on the Microsoft Windows platform. Availability: http://www.megasoftware.net.read more
Citations
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Ribosomal DNA Sequence Variation among Sympatric Strains of the Cyclotella meneghiniana Complex (Bacillariophyceae) Reveals Cryptic Diversity
TL;DR: The random distribution of ITS variation within four genetically distinct--apparently reproductively isolated--groups indicated that the genetic structure in Cyclotella meneghiniana can probably be explained by the presence of cryptic sexual species rather than by the lack of allogamous sexual reproduction.
Journal ArticleDOI
A novel anticancer and antifungus phenazine derivative from a marine actinomycete BM-17
TL;DR: A marine actinomycete, designated strain BM-17, was isolated from a sediment sample collected in the Arctic Ocean and showed significant antifungal activity against Candida albicans and high cancer cell cytotoxicity against HepG2, A549, HCT-116 and COC1 cells.
Journal ArticleDOI
Molecular phylogeny and evolution of prosimians based on complete sequences of mitochondrial DNAs.
Atsushi Matsui,Felix Rakotondraparany,Isao Munechika,Masami Hasegawa,Masami Hasegawa,Satoshi Horai +5 more
TL;DR: To estimates the speciation dates within primates, the amino acid sequences of mt-proteins were analyzed with a Bayesian method of Thorne and Kishino and the biogeographic scenarios which have been proposed for the origin of strepsirrhini and for the dispersal of the lemuriformes and lorisiformes were reexamined.
Journal ArticleDOI
The Association of Interleukin 6 Haplotype Clades With Mortality in Critically Ill Adults
TL;DR: Haplotype-based analysis succeeded in identifying this association between specific haplotype clades of IL-6 and increased mortality and more organ dysfunction in a cohort of critically ill patients who had SIRS, whereas individual single nucleotide polymorphism- based analysis failed.
Journal ArticleDOI
Aeromonas aquariorum sp. nov., isolated from aquaria of ornamental fish
Antonio J. Martínez-Murcia,Maria José Saavedra,Maria José Saavedra,V. R. Mota,V. R. Mota,T. Maier,Erko Stackebrandt,Sylvie Cousin +7 more
TL;DR: A novel species of the genus Aeromonas is described, for which the name AeromonAs aquariorum sp.
References
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Book
Molecular Evolution and Phylogenetics
Masatoshi Nei,Sudhir Kumar +1 more
TL;DR: This chapter discusses the molecular basis of evolution, the evolution of organisms based on the fossil record, and the implications of these events for phylogenetic inference.
Journal ArticleDOI
MEGA: Molecular Evolutionary Genetics Analysis software for microcomputers
TL;DR: In this program, various methods for estimating evolutionary distances from nucleotide and amino acid sequence data, three different methods of phylogenetic inference (UPGMA, neighbor-joining and maximum parsimony) and two statistical tests of topological differences are included.
Book
Molecular Evolution: A Phylogenetic Approach
TL;DR: The Archaeology of the Genome Trees Genes: Organization, Function and Evolution Genes in Populations Measuring Genetic Change Inferring Molecular Phylogeny Models of Molecular Evolution Applications of molecular phylogenetics as mentioned in this paper.
Journal ArticleDOI
Phylogenetic test of the molecular clock and linearized trees.
TL;DR: To estimate approximate divergence times of species or species groups with molecular data, a method of constructing a linearized tree under the assumption of a molecular clock is developed and used to analyze hominoid mitochondrial DNA and drosophilid Adh gene sequences.
Journal ArticleDOI
Molecular Evolution — A Phylogenetic Approach.
TL;DR: The authors set themselves the tasks of showing how evolutionary information is written into gene sequences and describing the methods by which such information can be recovered and succeed, providing a wealth of examples and setting many of them in a historical perspective.
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The neighbor-joining method: a new method for reconstructing phylogenetic trees.
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