MgO nanoparticles coated with polyethylene glycol as carrier for 2-Methoxyestradiol anticancer drug.
Aline Alfaro,Andrea León,Emanuel Guajardo-Correa,Patricia Reuquen,Francisco Torres,Mario Mery,Rodrigo Segura,Paula A. Zapata,Pedro A. Orihuela +8 more
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The MgO-PEG-2ME NPs decreased the viability of the prostate cancer cell line LNCap suggesting that this nanocomposite is suitable as a drug delivery system for anticancer prostate therapy.Abstract:
Novel Magnesium Oxide (MgO) nanoparticles (NPs) modified with the polymer polyethylene glycol (PEG) were synthesized as carrier for the anticancer drug 2-Methoxyestradiol (2ME) to improve its clinical application. The functionalized NPs were characterized by Infrared spectroscopy with Fourier transform to elucidate the vibration modes of this conjugate, indicating the formation of the MgO-PEG-2ME nanocomposite. The studies of absorption and liberation determined that MgO-PEG-2ME NPs incorporated 98.51 % of 2ME while liberation of 2ME was constant during 7 days at pH 2, 5 and 7.35. Finally, the MgO-PEG-2ME NPs decreased the viability of the prostate cancer cell line LNCap suggesting that this nanocomposite is suitable as a drug delivery system for anticancer prostate therapy.read more
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Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects
TL;DR: A novel review article introduces few frequently used capping agents in the fabrication of nanoparticles and recent advancements in biomedicine and environmental remediation approaches of capped nanoparticles have been elaborated.
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Green synthesized MgO nanoparticles infer biocompatibility by reducing in vivo molecular nanotoxicity in embryonic zebrafish through arginine interaction elicited apoptosis.
Suresh K. Verma,Suresh K. Verma,Kumari Nisha,Pritam Kumar Panda,Paritosh Patel,Puja Kumari,M.A. Mallick,Biplab Sarkar,Biswadeep Das +8 more
TL;DR: The study delineated the nanotoxicity of MgO NP and suggests the adoption and use of new green methodology for future production.
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Utilization of olive pomace in nano MgO modification for sorption of Ni(II) and Cu(II) metal ions from aqueous solutions
TL;DR: In this paper, a comparative study between Magnesium oxide nanoparticles and NMOOP700 material for the sorption of Cu (II) or Ni(II) ions was implemented.
Journal ArticleDOI
Synthesis, characterization, and antibacterial study of novel Mg0.9Cr0.05M0.05O (M = Co, Ag, Ni) nanocrystals
Tauseef Munawar,Muhammad Nadeem,Faisal Mukhtar,Adnan Azhar,Murtaza Hasan,Khalid Mahmood,Altaf Hussain,Adnan Ali,M.I. Arshad,Muhammad Ajaz un Nabi,Faisal Iqbal +10 more
TL;DR: In this article, the structural, electrical, and antibacterial properties of novel Mg0.95Cr0.05O and Mg 0.9Cr 0.5O nanocrystals were studied.
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Role of MgO nanoparticles in the suppression of Meloidogyne incognita, infecting cowpea and improvement in plant growth and physiology.
TL;DR: It could be inferred that MgO nanoparticles played twin roles, first as a nematicidal agent and the other as growth promotion inducer on cowpea infected with M. incognita.
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