Models of Self-Organizing Bacterial Communities and Comparisons with Experimental Observations
Americo Marrocco,Hervé Henry,I. B. Holland,Mathis Plapp,S. J. Seror,Benoît Perthame,Benoît Perthame +6 more
TLDR
A critical anal ysis of the validity of the model based on recent observations of the swarming bacteria which show that nutrients are not limitating but distinct subpopulations growing at different rates are lik ely present is presented.Abstract:
Bacillus subtilis swarms rapidly over the surface of a synthetic medium creating remarkable hyperbranched dendritic communities. Models to reproduce such effects have been proposed under the form of parabolic Partial Differential Equations representing the dynamics of the active cells (both motile and multiplying), the passive cells (non-motile and non-growing) and nutrient concentration. We test the numerical behavior of such models and compare them to relevant experimental data together with a critical analysis of the validity of the models based on recent observations of the swarming bacteria which show that nutrients are not limitating but distinct subpopulations growing at different rates are likely present.read more
Citations
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Travelling plateaus for a hyperbolic Keller–Segel system with attraction and repulsion: existence and branching instabilities
Benoît Perthame,Benoît Perthame,Christian Schmeiser,Min Tang,Min Tang,Nicolas Vauchelet,Nicolas Vauchelet +6 more
TL;DR: In this paper, the authors proposed a functional analysis framework for the hyperbolic Keller-Segel system with logistic sensitivity, where repulsive and attractive forces, acting on a conservative system, create stable travelling patterns or branching instabilities.
Journal ArticleDOI
Single-cell analysis in situ in a Bacillus subtilis swarming community identifies distinct spatially separated subpopulations differentially expressing hag (flagellin), including specialized swarmers.
Kassem Hamze,Sabine Autret,Krzysztof Hinc,Krzysztof Hinc,Soumaya Laalami,Daria Julkowska,Romain Briandet,Margareth Renault,Cédric Absalon,I. Barry Holland,Harald Putzer,Simone J. Séror +11 more
TL;DR: A model for this swarming process is discussed, emphasizing the importance of population density and of the complementary roles of packs of swarmers driving dendrite extension, while non-mobile cells in the stems extend dendrites by multiplication.
Journal ArticleDOI
The effects of chemical interactions and culture history on the colonization of structured habitats by competing bacterial populations
Simon van Vliet,Simon van Vliet,Simon van Vliet,Felix J. H. Hol,Tim Weenink,Tim Weenink,Peter Galajda,Juan E. Keymer,Juan E. Keymer +8 more
TL;DR: The colonization of spatially structure habitats by two interacting populations can lead to the formation of complex, but reproducible, spatiotemporal patterns and it is shown that chemical interactions between two populations cause them to remain spatially segregated while they compete for habitat space.
Journal ArticleDOI
Waves for a hyperbolic keller–segel model and branching instabilities
Fiammetta Cerreti,Benoît Perthame,Benoît Perthame,Christian Schmeiser,Min Tang,Nicolas Vauchelet,Nicolas Vauchelet +6 more
TL;DR: A new class of models is presented which is compatible with the experimental observations and which predict branching instabilities and does not use nutrient limitation and is based on numerical simulations.
Journal ArticleDOI
The role of intracellular signaling in the stripe formation in engineered Escherichia coli populations
Xiaoru Xue,Chuan Xue,Min Tang +2 more
TL;DR: A detailed hybrid model that treats each cell as an individual particle and incorporates intracellular signaling via an internal ODE system is developed and a mean-field PDE model is derived from the hybrid model using asymptotic analysis.
References
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Journal Article
Two-dimensional Keller-Segel model: Optimal critical mass and qualitative properties of the solutions
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Journal ArticleDOI
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P. Gray,Stephen K. Scott +1 more
TL;DR: In this paper, the authors consider the simple case of uniform temperatures and concentrations in the isothermal CSTR and the simplest of reaction schemes: (i) quadratic autocatalysis (A + B →2 B ); and (ii) cubic autoccatalysis ( A + 2 B →3 B ).