Journal ArticleDOI
Neuroimaging studies of mood disorders.
TLDR
Findings implicate interconnected neural circuits in which pathologic patterns of neurotransmission may result in the emotional, motivational, cognitive, and behavioral manifestations of primary and secondary affective disorders.About:
This article is published in Biological Psychiatry.The article was published on 2000-10-15. It has received 1280 citations till now. The article focuses on the topics: Prefrontal cortex & Mood disorders.read more
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Journal ArticleDOI
Placebo-induced changes in FMRI in the anticipation and experience of pain.
Tor D. Wager,James K. Rilling,Edward E. Smith,Alex Sokolik,Kenneth L. Casey,Richard J. Davidson,Stephen M. Kosslyn,Robert M. Rose,Jonathan D. Cohen +8 more
TL;DR: fMRI experiments found that placebo analgesia was related to decreased brain activity in pain-sensitive brain regions, including the thalamus, insula, and anterior cingulate cortex, and was associated with increased activity during anticipation of pain in the prefrontal cortex, providing evidence that placebos alter the experience of pain.
Journal ArticleDOI
Neurobiology of emotion perception II: Implications for major psychiatric disorders
TL;DR: It is suggested that distinct patterns of structural and functional abnormalities in neural systems important for emotion processing are associated with specific symptoms of schizophrenia and bipolar and major depressive disorder.
Journal ArticleDOI
Neurocircuitry of Mood Disorders
Joseph L. Price,Wayne C. Drevets +1 more
TL;DR: A system has been described that links the medial prefrontal cortex and a few related cortical areas to the amygdala, the ventral striatum and pallidum, the medial thalamus, the hypothalamus, and the periaqueductal gray and other parts of the brainstem, which indicates that this system is centrally involved in mood disorders.
Journal ArticleDOI
The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice.
Premysl Bercik,Emmanuel Denou,Josh Collins,Wendy Jackson,Jun Lu,Jennifer Jury,Yikang Deng,Patricia Blennerhassett,Joseph Macri,Kathy D. McCoy,Elena F. Verdu,Stephen M. Collins +11 more
TL;DR: The intestinal microbiota influences brain chemistry and behavior independently of the autonomic nervous system, gastrointestinal-specific neurotransmitters, or inflammation.
Journal ArticleDOI
The Experience of Emotion
TL;DR: This chapter outlines an emerging scientific agenda for understanding what experiences of emotion feel like and how they arise, and the role of such experiences in the economy of the mind and behavior.
References
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Book
The Cognitive Neurosciences
TL;DR: The fourth edition of The Cognitive Neurosciences continues to chart new directions in the study of the biologic underpinnings of complex cognition -the relationship between the structural and physiological mechanisms of the nervous system and the psychological reality of the mind as discussed by the authors.
The Emotional Brain
TL;DR: In The Emotional Brain, Joseph LeDoux investigates the origins of human emotions and explains that many exist as part of complex neural systems that evolved to enable us to survive.
Book
Psychopharmacology: The Fourth Generation of Progress
Floyd E. Bloom,David J. Kupfer +1 more
TL;DR: Part 1 Preclinical section: critical analysis of methods transmitter systems - amino acids, amines, peptides, new transmitterscritical analysis of integrative concepts.
Journal ArticleDOI
The cerebellar cognitive affective syndrome.
TL;DR: A constellation of deficits is suggestive of disruption of the Cerebellar modulation of neural circuits that link prefrontal, posterior parietal, superior temporal and limbic cortices with the cerebellum, called the 'cerebellar cognitive affective syndrome'.