Neurological Complications of COVID-19: Guillain-Barre Syndrome Following Pfizer COVID-19 Vaccine
TLDR
Wang et al. as discussed by the authors reported a case of Guillain-Barre syndrome (GBS) after receiving the first dose of Pfizer - COVID-19 vaccine.Abstract:
Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in Wuhan, China, in December 2019, Coronavirus - 19 (COVID-19) has become a global pandemic with multiple neurological complications. In December 2020, two vaccines have been approved in the United States for the prevention of COVID-19. We report a case of Guillain-Barre Syndrome (GBS) after receiving the first dose of Pfizer - COVID-19 vaccine.read more
Citations
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Guillain-Barré syndrome following ChAdOx1-S/nCoV-19 vaccine.
Boby Varkey Maramattom,Parameswaran Krishnan,Reji Paul,Sandeep Padmanabhan,Soumya Cherukudal Vishnu Nampoothiri,Akheel A. Syed,Halinder S. Mangat +6 more
TL;DR: In this article, the authors observed seven cases of Guillain-Barre syndrome (GBS) that occurred within 2 weeks of the first dose of vaccination and all seven patients developed severe GBS.
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Spectrum of neurological complications following COVID-19 vaccination.
TL;DR: A wide spectrum of neurological complications is continuously being reported following COVID-19 vaccination, such as cerebral venous sinus thrombosis, acute transverse myelitis, acute disseminated encephalomyelitis and acute demyelinating polyneuropathy.
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Guillain-Barre syndrome following the first dose of the chimpanzee adenovirus-vectored COVID-19 vaccine, ChAdOx1.
TL;DR: In this paper, the authors presented an interesting case of a 37-year-old man who, 3 weeks following his first dose of the chimpanzee adenovirus-vectored COVID-19 vaccine, ChAdOx1, presented to hospital with a rapidly progressive ascending muscle weakness and back pain in the absence of any other triggers.
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COVID-19 mRNA vaccination leading to CNS inflammation: a case series.
Mahsa Khayat-Khoei,Shamik Bhattacharyya,Joshua Katz,Daniel Harrison,Shahamat Tauhid,Penny Bruso,Maria K. Houtchens,Keith R. Edwards,Rohit Bakshi +8 more
TL;DR: In this paper, clinical and MRI features of seven individuals who received the Moderna (n = 3) or Pfizer (n= 4) SARS-CoV-2 mRNA vaccines were reported.
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Case of Guillain-Barré syndrome following COVID-19 vaccine.
TL;DR: In this article, the authors describe a case of a 62-year-old woman who presented with paraesthesia and progressive weakness of both lower limbs over three days, and the diagnosis of Guillain-Barre syndrome (GBS) was confirmed by lumbar puncture and nerve conduction studies.
References
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Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.
Fernando P. Polack,Stephen J. Thomas,Nicholas Kitchin,Judith Absalon,Alejandra Gurtman,Stephen Lockhart,John L. Perez,Gonzalo Pérez Marc,Edson D. Moreira,Cristiano Zerbini,Ruth Bailey,Kena A. Swanson,Satrajit Roychoudhury,Kenneth Koury,Ping Li,Warren Kalina,David A. Cooper,Robert W. Frenck,Laura L. Hammitt,Özlem Türeci,Haylene Nell,Axel Schaefer,Serhat Ünal,Dina B. Tresnan,Susan Mather,Philip R. Dormitzer,Ugur Sahin,Kathrin U. Jansen,William C. Gruber +28 more
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TL;DR: In this paper, a comprehensive post-efficacy strategy for the next steps to ensure vaccination of the global population is now required, including how to manufacture billions of doses of high-quality vaccines, support for vaccine purchase, coordination of supply, equitable distribution of vaccines and the logistics of global vaccine delivery, all of which are a prelude to a massive vaccination campaign targeting people of all ages.
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COVID-19-associated Guillain-Barré syndrome: The early pandemic experience.
James B. Caress,Ryan Castoro,Zachary Simmons,Stephen N. Scelsa,Richard A. Lewis,Aditi Ahlawat,Pushpa Narayanaswami +6 more
TL;DR: GBS‐associated COVID‐19 appears to be an uncommon condition with similar clinical and EDx patterns to GBS before the pandemic, and future studies should compare patients with COvid‐19–associated GBS to those with contemporaneous non–COVID‐ 19 GBS and determine whether the incidence of GBS is elevated in those with CO VID‐19.
Journal ArticleDOI
Vaccines and Guillain-Barré Syndrome
TL;DR: There is little evidence to support a causal association with most vaccines, but the benefit of vaccines in preventing disease and decreasing morbidity and mortality, particularly for influenza, needs to be weighed against the potential risk of GBS.
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