Journal ArticleDOI
Neuronal circuits of the neocortex
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TLDR
It is found that, as has long been suspected by cortical neuroanatomists, the same basic laminar and tangential organization of the excitatory neurons of the neocortex is evident wherever it has been sought.Abstract:
We explore the extent to which neocortical circuits generalize, i.e., to what extent can neocortical neurons and the circuits they form be considered as canonical? We find that, as has long been suspected by cortical neuroanatomists, the same basic laminar and tangential organization of the excitatory neurons of the neocortex is evident wherever it has been sought. Similarly, the inhibitory neurons show characteristic morphology and patterns of connections throughout the neocortex. We offer a simple model of cortical processing that is consistent with the major features of cortical circuits: The superficial layer neurons within local patches of cortex, and within areas, cooperate to explore all possible interpretations of different cortical input and cooperatively select an interpretation consistent with their various cortical and subcortical inputs.read more
Citations
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Journal ArticleDOI
Geometric and functional organization of cortical circuits.
Gordon M. Shepherd,Armen Stepanyants,Armen Stepanyants,Ingrid Bureau,Ingrid Bureau,Dmitri B. Chklovskii,Karel Svoboda,Karel Svoboda +7 more
TL;DR: A large plasticity potential appears to be incorporated into these circuits, allowing for functional 'tuning' with fixed axonal and dendritic arbor geometry.
Book
Computational Maps in the Visual Cortex
TL;DR: This paper describes the development of Maps and Connections and the construction of LISSOM, a Computational Map Model of V1, and the role of plasticity, Hierarchical Model in this development.
Journal ArticleDOI
Oscillatory phase coupling coordinates anatomically dispersed functional cell assemblies
Ryan T. Canolty,Karunesh Ganguly,Steven W. Kennerley,Charles F. Cadieu,Kilian Koepsell,Jonathan D. Wallis,Jose M. Carmena +6 more
TL;DR: It is shown that spiking activity in single neurons and neuronal ensembles depends on dynamic patterns of oscillatory phase coupling between multiple brain areas, in addition to the effects of proximal LFP phase, which suggests that neuronal oscillations enable selective and dynamic control of distributed functional cell assemblies.
Journal ArticleDOI
Burst Spiking of a Single Cortical Neuron Modifies Global Brain State
Chengyu Li,Mu-ming Poo,Yang Dan +2 more
TL;DR: It is reported that repetitive high-frequency burst spiking of a single rat cortical neuron could trigger a switch between the cortical states resembling slow-wave and rapid–eye-movement sleep, pointing to the power of single cortical neurons in modulating the behavioral state of an animal.
Journal ArticleDOI
A transcriptomic atlas of mouse neocortical layers.
T. Grant Belgard,Ana C. Marques,Peter L. Oliver,Hatice Ozel Abaan,Tamara Sirey,Anna Hoerder-Suabedissen,Fernando García-Moreno,Zoltán Molnár,Elliott H. Margulies,Chris P. Ponting +9 more
TL;DR: This new resource greatly extends currently available resources, such as the Allen Mouse Brain Atlas and microarray data sets, by providing quantitative expression levels, by being genome-wide, by including novel loci, and by identifying candidate alternatively spliced transcripts that are differentially expressed across layers.
References
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Neuromorphic electronic systems
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