Journal ArticleDOI
Neuronal circuits of the neocortex
Reads0
Chats0
TLDR
It is found that, as has long been suspected by cortical neuroanatomists, the same basic laminar and tangential organization of the excitatory neurons of the neocortex is evident wherever it has been sought.Abstract:
We explore the extent to which neocortical circuits generalize, i.e., to what extent can neocortical neurons and the circuits they form be considered as canonical? We find that, as has long been suspected by cortical neuroanatomists, the same basic laminar and tangential organization of the excitatory neurons of the neocortex is evident wherever it has been sought. Similarly, the inhibitory neurons show characteristic morphology and patterns of connections throughout the neocortex. We offer a simple model of cortical processing that is consistent with the major features of cortical circuits: The superficial layer neurons within local patches of cortex, and within areas, cooperate to explore all possible interpretations of different cortical input and cooperatively select an interpretation consistent with their various cortical and subcortical inputs.read more
Citations
More filters
Journal ArticleDOI
Inhibition and brain work
TL;DR: Issues relevant to an assessment of the work performed by inhibitory interneurons in the service of brain function are examined.
Journal ArticleDOI
An integrated micro- and macroarchitectural analysis of the Drosophila brain by computer-assisted serial section electron microscopy.
Albert Cardona,Stephan Saalfeld,Stephan Preibisch,Benjamin Schmid,Anchi Cheng,J. Pulokas,Pavel Tomancak,Volker Hartenstein +7 more
TL;DR: This study applies the software package TrakEM2 to reconstruct neuronal microcircuitry from TEM sections of a small brain, the early larval brain of Drosophila melanogaster, and describes the network motifs most frequently encountered in the Drosophile neuropile.
Journal ArticleDOI
Timing, Timing, Timing: Fast Decoding of Object Information from Intracranial Field Potentials in Human Visual Cortex
TL;DR: This work quantified at millisecond resolution the amount of visual information conveyed by intracranial field potentials from 912 electrodes in 11 human subjects and suggested that physiological activity in the temporal lobe can account for key properties of visual recognition.
Journal ArticleDOI
Hierarchical organization of cortical and thalamic connectivity
Julie A. Harris,Stefan Mihalas,Karla E. Hirokawa,Jennifer D. Whitesell,Hannah Choi,Hannah Choi,Amy Bernard,Phillip Bohn,Shiella Caldejon,Linzy Casal,Andrew Cho,Aaron Feiner,David Feng,Nathalie Gaudreault,Charles R. Gerfen,Nile Graddis,Peter A. Groblewski,Alex M. Henry,Anh Ho,Robert Howard,Joseph E. Knox,Leonard Kuan,Xiuli Kuang,Jérôme Lecoq,Phil Lesnar,Yaoyao Li,Jennifer Luviano,Stephen McConoughey,Marty Mortrud,Maitham Naeemi,Lydia Ng,Seung Wook Oh,Benjamin Ouellette,Elise Shen,Staci A. Sorensen,Wayne Wakeman,Quanxin Wang,Yun Wang,Ali Williford,John W. Phillips,Allan R. Jones,Christof Koch,Hongkui Zeng +42 more
TL;DR: Using mouse lines in which subsets of neurons are genetically labelled, the authors provide generalized anatomical rules for connections within and between the cortex and thalamus, showing that cell-class-specific connections are organized in a shallow hierarchy within the mouse corticothalamic network.
Journal ArticleDOI
The Cell-Type Specific Cortical Microcircuit: Relating Structure and Activity in a Full-Scale Spiking Network Model
TL;DR: The integration of a large body of the available connectivity data enables us to expose the dynamical consequences of the cortical microcircuitry.
References
More filters
Journal ArticleDOI
Receptive fields, binocular interaction and functional architecture in the cat's visual cortex
David H. Hubel,Torsten N. Wiesel +1 more
TL;DR: This method is used to examine receptive fields of a more complex type and to make additional observations on binocular interaction and this approach is necessary in order to understand the behaviour of individual cells, but it fails to deal with the problem of the relationship of one cell to its neighbours.
Journal ArticleDOI
Distributed Hierarchical Processing in the Primate Cerebral Cortex
TL;DR: A summary of the layout of cortical areas associated with vision and with other modalities, a computerized database for storing and representing large amounts of information on connectivity patterns, and the application of these data to the analysis of hierarchical organization of the cerebral cortex are reported on.
Journal ArticleDOI
Hierarchical models of object recognition in cortex
TL;DR: A new hierarchical model consistent with physiological data from inferotemporal cortex that accounts for this complex visual task and makes testable predictions is described.
Journal ArticleDOI
Neuromorphic electronic systems
TL;DR: It is shown that for many problems, particularly those in which the input data are ill-conditioned and the computation can be specified in a relative manner, biological solutions are many orders of magnitude more effective than those using digital methods.
Journal ArticleDOI