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O colágeno em fáscia transversal de pacientes com hérnia inguinal direta submetidos à videolaparoscopia

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TLDR
The direct inguinal hernia patients have less collagen in transversalis fascia either absolutely or relatively to other constitutional elements, stablishing that there are less collagenIn the hernia's wall.
Abstract
OBJETIVO: Analisar quanto a espessura, elementos constitutivos e quantificacao do colageno total amostras de fascias transversais de pacientes entre 20 e 60 anos de idade, com hernia inguinal direta, coletadas no momento da correcao videolaparoscopica, comparando-as com amostras do mesmo tecido, retiradas de cadaveres. METODOS: Biopsias de 23 pacientes e de 22 cadaveres foram analisadas e comparadas. Utilizaram-se as tecnicas de coloracao de Hematoxilina-Eosina e Picrosirius. As imagens captadas foram analisadas por tecnica videomorfometrica assistida por computador. RESULTADOS: Constatou-se uma espessura de fascia transversal nos controles, em media, de 4.5 milimetros. A espessura da fascia transversal dos pacientes com hernia foi, em media, 58 % menor (p< 0.001). Nao se evidenciou algum processo de degeneracao das fibras de colageno atribuivel a senilidade. O principal elemento constitutivo da fascia, nos dois grupos, foi o tecido conjuntivo denso, representando cerca de 75 % nos controles e sendo um terco menor nos pacientes (p< 0.001). A area media percentual de colageno no campo amostral dos pacientes encontrada foi metade da area dos controles (p< 0.001), resultando em uma menor quantidade de colageno na parede posterior herniada. CONCLUSAO: Os pacientes com hernia inguinal direta apresentam menor quantidade de colageno tanto absoluta quanto relativamente aos demais elementos constitutivos da fascia transversal.

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Journal ArticleDOI

Immunohistochemical evaluation of fibrillar components of the extracellular matrix of transversalis fascia and anterior abdominal rectus sheath in men with inguinal hernia.

TL;DR: The amount of fibrillar extracellular matrix components did not change in patients with and without inguinal hernia, and no statistically significant differences were found in the amount of elastic fibers, collagen I and collagen III among patients with inguinals hernia when compared with subjects without hernia.
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Linea alba collagen assessment in morbidly obese patients

TL;DR: The amount of collagen in the linea alba above the umbilical region in the morbidly obese patients was smaller than in the non-obese cadavers in the same age group.
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The use of mesh and collagen in incisional hernias.

TL;DR: The authors claim that the routine use of synthetic mesh is not justiWed because of its potential for complications, and that the results of sutured repair of small to medium-sized hernias are satisfactory, but according to a well-conducted randomized controlled trial that compared suture versus mesh repair of incisional hernia in patients with a primary or Wrst-time recurrent incisionAL hernia, the conclusion was that theoutine use of mesh is superior to suture repair

Hérnia inguinal: Considerações sobre a Etiologia e o Tratamento

TL;DR: A incidência e o diagnostico de hérnia oculta contra-lateral antes da correção cirúrgica é muito vantajoso tanto for a sua correptão no mesmo tempo cirúRGico evitando novo procedimento cirudrgico e implicações econômicas e de risco cirúrhico.
References
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Journal ArticleDOI

Comparison of Conventional Anterior Surgery and Laparoscopic Surgery for Inguinal-Hernia Repair

TL;DR: Patients with inguinal hernias who undergo laparoscopic repair recover more rapidly and have fewer recurrences than those who undergo open surgical repair.
Journal ArticleDOI

Increases in type III collagen gene expression and protein synthesis in patients with inguinal hernias.

TL;DR: This study represents the first attempt to define individuals with an abnormality in collagen production that may be specifically related to herniation, and suggests a constitutive and systemic increase in type III collagen synthesis may result in reduced collagen fibril assembly in the abdominal wall, eventually leading to the development of hernia.
Journal ArticleDOI

Inguinal hernia repair in adults