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Orthomyxoviridae: The Viruses and Their Replication.
Robert A. Lamb
- Vol. 2, pp 1647-1689
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The article was published on 1996-01-01 and is currently open access. It has received 3135 citations till now. The article focuses on the topics: Viral replication & Orthomyxoviridae.read more
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European Position Paper on Rhinosinusitis and Nasal Polyps 2020
Wytske Fokkens,Valerie J. Lund,Joachim Mullol,Claus Bachert,Isam Alobid,Fuad M. Baroody,Noam A. Cohen,Anders Cervin,Richard Douglas,Philippe Gevaert,Christos Georgalas,Herman Goossens,Richard J. Harvey,Peter Hellings,Claire Hopkins,Nick Jones,Guy Joos,Livije Kalogjera,Bob Kern,Marek L. Kowalski,David Price,Herbert Riechelmann,Rodney J. Schlosser,Brent A. Senior,Mike Thomas,Elina Toskala,Richard Louis Voegels,De Yun Wang,Peter-John Wormald +28 more
TL;DR: The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012 and addresses areas not extensively covered in EPOS2012 such as paediatric CRS and sinus surgery.
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A newly discovered human pneumovirus isolated from young children with respiratory tract disease.
Bernadette G. van den Hoogen,Jan C. de Jong,Jan Groen,Thijs Kuiken,Ronald de Groot,Ron A. M. Fouchier,Albert D. M. E. Osterhaus +6 more
TL;DR: Serological studies showed that by the age of five years, virtually all children in the Netherlands have been exposed to human metapneumovirus and that the virus has been circulating in humans for at least 50 years.
Journal ArticleDOI
The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus
Abraham L. Brass,Abraham L. Brass,Abraham L. Brass,I-Chueh Huang,Yair Benita,Sinu P. John,Manoj N. Krishnan,Eric M. Feeley,Bethany J. Ryan,Jessica L. Weyer,Louise van der Weyden,Erol Fikrig,David J. Adams,Ramnik J. Xavier,Michael Farzan,Stephen J. Elledge +15 more
TL;DR: It is discovered that the interferon-inducible transmembrane proteins IFITM1, 2, and 3 restrict an early step in influenza A viral replication.
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Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
TL;DR: Recent findings suggest that the association of cleavage/polyadenylation factors with the transcriptional complex via the carboxyl-terminal domain of the RNA polymerase II (Pol II) large subunit is the means by which the cell restricts polyadenylations to Pol II transcripts.
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The multifunctional NS1 protein of influenza A viruses.
TL;DR: The basic biochemistry of NS1 is summarized, in particular its synthesis, structure, and intracellular localization, and the various roles NS1 has in regulating viral replication mechanisms, host innate/adaptive immune responses, and cellular signalling pathways are discussed.