Osteoimmunomodulation for the development of advanced bone biomaterials
Zetao Chen,Travis J. Klein,Rachael Z. Murray,Ross Crawford,Jiang Chang,Jiang Chang,Chengtie Wu,Chengtie Wu,Yin Xiao +8 more
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TLDR
In this article, the importance of the immune response during biomaterial-mediated osteogenesis was recognized and the paradigm shift of bone biomaterials to an osteo-immunomodulatory material was proposed.About:
This article is published in Materials Today.The article was published on 2016-07-01 and is currently open access. It has received 462 citations till now. The article focuses on the topics: Osteoimmunology.read more
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Biodegradable Magnesium-Based Implants in Orthopedics-A General Review and Perspectives.
TL;DR: Progress made on the development of Mg‐based implants in basic, translational, and clinical research has laid down a foundation for developing a new era in the treatment of challenging and prevalent bone diseases.
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Tuning Chemistry and Topography of Nanoengineered Surfaces to Manipulate Immune Response for Bone Regeneration Applications
Zetao Chen,Zetao Chen,Akash Bachhuka,Shengwei Han,Fei Wei,Shifeier Lu,Rahul Madathiparambil Visalakshan,Krasimir Vasilev,Yin Xiao,Yin Xiao +9 more
TL;DR: This study found that tuning the surface chemistry and scale of the nanotopography significantly modulated the osteoimmune environment, including changes in the expression of inflammatory cytokines, osteoclastic activities, and osteogenic, angiogenic, and fibrogenic factors.
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Current Advances in Immunomodulatory Biomaterials for Bone Regeneration.
TL;DR: An overview of biomaterial‐mediated modulation of the immune response for regulating key bone regeneration events, such as osteogenesis, osteoclastogenesis, and inflammation is provided and how these strategies can be utilized for future bone tissue engineering applications are discussed.
Journal ArticleDOI
A multifaceted coating on titanium dictates osteoimmunomodulation and osteo/angio-genesis towards ameliorative osseointegration.
Long Bai,Zhibin Du,Jingjing Du,Wei Yao,Jia-Ming Zhang,Zeming Weng,Si Liu,Ya Zhao,Yanlian Liu,Xiangyu Zhang,Xiaobo Huang,Xiaohong Yao,Ross Crawford,Ruiqiang Hang,Di Huang,Bin Tang,Yin Xiao +16 more
TL;DR: In this article, a microporous TiO 2 coating decorated with hydroxyapatite (HA) nanoparticles was generated by micro-arc oxidation of pure titanium (Ti) and followed annealing.
Mediation of biomaterial-cell interactions by adsorbed proteins: A review
TL;DR: In this article, a review illustrates the mediation of cell responses to biomaterials by adsorbed proteins, in the context of osteoblasts and selected materials used in orthopedic implants and bone tissue engineering.
References
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