Oxidative stress effect on progesterone-induced blocking factor (PIBF) binding to PIBF-receptor in lymphocytes.
Carlos de la Haba,J.R. Palacio,Tamas Palkovics,Julia Szekeres-Bartho,Antoni Morros,Paz Martínez +5 more
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TLDR
In this article, a new procedure has been developed which quantitatively analyzes the regionalization of a membrane receptor among the lipid domains of different fluidity in the plasma membrane, which is related to an increase of lipid raft clustering.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 2014-01-01 and is currently open access. It has received 7 citations till now. The article focuses on the topics: Membrane fluidity & Lipid raft.read more
Citations
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Journal ArticleDOI
Progesterone-Related Immune Modulation of Pregnancy and Labor.
TL;DR: The role of P4 as a modulator of inflammation, both systemic and intrinsic to the uterus, during human pregnancy and labor is dissected.
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Hormonal Regulation of Physiology, Innate Immunity and Antibody Response to H1N1 Influenza Virus Infection During Pregnancy.
TL;DR: Advances in the field of reproductive immunology in response to viral infection are highlighted and how that knowledge might be used to develop more effective post-infection therapies and vaccination strategies are illustrated.
Journal ArticleDOI
Restoring effect of selenium on the molecular content, structure and fluidity of diabetic rat kidney brush border cell membrane.
TL;DR: The study suggests that medium and, more predominantly, low-dose selenium treatment can be efficient in eliminating diabetes-induced structural alterations.
Journal ArticleDOI
Proliferative and Invasive Effects of Progesterone-Induced Blocking Factor in Human Glioblastoma Cells.
TL;DR: Data suggest that PIBF promotes proliferation, migration, and invasion of human glioblastoma cells.
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LPS-Induced Macrophage Activation and Plasma Membrane Fluidity Changes are Inhibited Under Oxidative Stress
TL;DR: Under oxidative conditions macrophage proinflammatory response might develop in an inefficient manner, and membrane fluidity modifications and cell function under oxidative stress in LPS-activated macrophages is analyzed.
References
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Journal ArticleDOI
Lipid rafts and signal transduction
Kai Simons,Derek Toomre +1 more
TL;DR: It is now becoming clear that lipid micro-environments on the cell surface — known as lipid rafts — also take part in this process of signalling transduction, where protein–protein interactions result in the activation of signalling cascades.
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Lipid rafts reconstituted in model membranes.
Christian Dietrich,Luis A. Bagatolli,Zoya Volovyk,Nancy L. Thompson,Moshe Levi,Ken Jacobson,Enrico Gratton +6 more
TL;DR: The notion that in biomembranes selected lipids could laterally aggregate to form more ordered, detergent-resistant lipid rafts into which glycosphingolipid- and cholesterol-rich lipid domains partition is strongly supported by this study.
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Lipid rafts: at a crossroad between cell biology and physics.
TL;DR: The concept of lipid rafts as it has emerged from the study of synthetic membranes with the reality of lateral heterogeneity in biological membranes is compared.
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Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation.
John M. Denu,Kirk G. Tanner +1 more
TL;DR: This study explores the proposal that PTPs may be regulated by reversible reduction/oxidation involving cellular oxidants such as hydrogen peroxide (H2O2) and proposes a chemical mechanism for reversible inactivation involving a cysteine sulfenic acid intermediate.
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Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions
TL;DR: These aldehydes exhibit great reactivity with biomolecules, such as proteins, DNA, and phospholipids, generating a variety of intra and intermolecular covalent adducts, which can diffuse within or even escape from the cell and attack targets far from the site of the original event.
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Mitogenic agents induce redistribution of transferrin receptors from internal pools to the cell surface.
Diane M. Ward,Jerry Kaplan +1 more