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Journal ArticleDOI

Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges.

TLDR
The state‐of‐the‐art on this subject is offered in order to develop new insights and to promote cooperative efforts in the fascinating field of API salt and cocrystal forms.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2017-08-01. It has received 186 citations till now.

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Journal ArticleDOI

Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications

TL;DR: Intensification of cocrystal research efforts has been accompanied by an expansion of the potential applications where cocrystals can offer a benefit, with particular emphasis placed on emerging technologies that can offer environmentally attractive and efficient applications.
Journal ArticleDOI

Advances in Oral Drug Delivery.

TL;DR: In this article, a review of the physiological, and pharmaceutical barriers influencing drug bioavailability for the oral route of administration, as well as the conventional and novel drug delivery strategies are discussed.
Journal ArticleDOI

Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals - A comprehensive review.

TL;DR: A comprehensive state‐of‐the‐art review on scCO2‐based processes focused on the formation and on the control of the physicochemical, structural and morphological properties of amorphous/crystalline pure drug nanoparticles.
Journal ArticleDOI

Pharmaceutical Cocrystal Drug Products: An Outlook on Product Development

TL;DR: In this review, the process of developing a pharmaceutical cocrystal drug product from screening to approval is described, with an emphasis on significant developments over the past decade.
Journal ArticleDOI

Pharmaceutical cocrystallization techniques. Advances and challenges.

TL;DR: The aim of this review is to present an extensive overview of the cocrystallization methods, focusing in the specificities of each technique, its advantages and disadvantages, divided into solvent‐based and solvent‐free methods.
References
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Journal ArticleDOI

First principles methods using CASTEP

TL;DR: The CASTEP program as mentioned in this paper is a computer program for first principles electro-Nic structure calculations, and some of its features and capabilities are described and near-future development plans outlined.
Journal ArticleDOI

The hydrogen bond in the solid state.

TL;DR: The hydrogen bond is the most important of all directional intermolecular interactions, operative in determining molecular conformation, molecular aggregation, and the function of a vast number of chemical systems ranging from inorganic to biological.
Book

An Introduction to Hydrogen Bonding

TL;DR: In this paper, the authors discuss the properties of strong and moderate hydrogen bonds in biological molecules and include inclusion of inclusion compounds in the graph set theory of graph set theories, which is used in this paper.
Journal ArticleDOI

SUPERFLIP– a computer program for the solution of crystal structures by charge flipping in arbitrary dimensions

TL;DR: SUPERFLIP is a computer program that can solve crystal structures from diffraction data using the recently developed charge-flipping algorithm and has been successfully compiled and tested on a variety of operating systems.
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