Pre-pregnancy body mass index in relation to infant birth weight and offspring overweight/obesity: a systematic review and meta-analysis.
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TLDR
Sensitivity analyses revealed that sample size, study method, quality grade of study, source of pre-pregnancy BMI or BW had a strong impact on the association between pre-Pregnancy obesity and LGA and subsequent offspring overweight/obesity.Abstract:
Background
Overweight/obesity in women of childbearing age is a serious public-health problem. In China, the incidence of maternal overweight/obesity has been increasing. However, there is not a meta-analysis to determine if pre-pregnancy body mass index (BMI) is related to infant birth weight (BW) and offspring overweight/obesity.read more
Citations
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Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child
TL;DR: Increased prepregnancy maternal insulin resistance and accompanying hyperinsulinemia, inflammation, and oxidative stress seem to contribute to early placental and fetal dysfunction in obese women.
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Preconceptional and maternal obesity: epidemiology and health consequences.
Lucilla Poston,Rishiraj Caleyachetty,Sven Cnattingius,Camila Corvalán,Ricardo Uauy,Ricardo Uauy,Sharron Herring,Matthew W. Gillman +7 more
TL;DR: For women who are already obese, renewed efforts should be made towards improved management during pregnancy, especially of blood glucose, and increased attention to post-partum weight management.
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Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews
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Influence of maternal obesity on the long-term health of offspring.
Keith M. Godfrey,Rebecca M. Reynolds,Susan L. Prescott,Moffat J. Nyirenda,Moffat J. Nyirenda,Vincent W. V. Jaddoe,Johan G. Eriksson,Birit F.P. Broekman,Birit F.P. Broekman,Birit F.P. Broekman +9 more
TL;DR: There is an urgent need for studies on causality, underlying mechanisms, and effective interventions to reverse the epidemic of obesity in women of childbearing age and to mitigate consequences for offspring.
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Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes
LifeCycle Project-Maternal Obesity,Ellis Voerman,Susana Santos,Susana Santos,Hazel Inskip,Pilar Amiano,Henrique Barros,Henrique Barros,Marie-Aline Charles,Marie-Aline Charles,Marie-Aline Charles,Leda Chatzi,George P. Chrousos,Eva Corpeleijn,Sarah Crozier,Myriam Doyon,Merete Eggesbø,Maria Pia Fantini,Sara Farchi,Francesco Forastiere,Vagelis Georgiu,Davide Gori,Wojciech Hanke,Irva Hertz-Picciotto,Irva Hertz-Picciotto,Barbara Heude,Barbara Heude,Marie-France Hivert,D. Hryhorczuk,Carmen Iñiguez,Anne M. Karvonen,Leanne K. Küpers,Hanna Lagström,Debbie A Lawlor,Irina Lehmann,Per Magnus,Renata Majewska,Johanna Mäkelä,Yannis Manios,Monique Mommers,Monique Mommers,Camilla Schmidt Morgen,George Moschonis,Ellen A. Nohr,Anne-Marie Nybo Andersen,Emily Oken,Agnieszka Pac,Eleni Papadopoulou,Eleni Papadopoulou,Juha Pekkanen,Costanza Pizzi,Kinga Polańska,Daniela Porta,Lorenzo Richiardi,Sheryl L. Rifas-Shiman,Nel Roeleveld,L. Ronfani,Ana Cristina Santos,M. Standl,Hein Stigum,Hein Stigum,Camilla Stoltenberg,E. Thiering,Carel Thijs,Maties Torrent,Tomas Trnovec,Marleen M.H.J. van Gelder,Lenie van Rossem,Andrea von Berg,Martine Vrijheid,Alet H. Wijga,Oleksandr Zvinchuk,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Keith M. Godfrey,Vincent W. V. Jaddoe,Romy Gaillard +76 more
TL;DR: In this meta-analysis of pooled individual participant data from 25 cohort studies, the risk for adverse maternal and infant outcomes varied by gestational weight gain and across the range of prepregnancy weights, however, the optimal gestations weight gain ranges had limited predictive value for the outcomes assessed.
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