Journal ArticleDOI
Preoperative gadoxetic acid–enhanced MRI for predicting microvascular invasion in patients with single hepatocellular carcinoma
TLDR
A combination of two or more of the following; arterial per itumoral enhancement, non-smooth tumor margin, and peritumoral hypointensity on hepatobiliary phase, can be used as a preoperative imaging biomarker for predicting MVI, with specificity >90%, and is associated with early recurrence after surgery of single HCC.About:
This article is published in Journal of Hepatology.The article was published on 2017-09-01. It has received 257 citations till now. The article focuses on the topics: Gadoxetic acid.read more
Citations
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Journal ArticleDOI
Prognostic and Therapeutic Implications of Microvascular Invasion in Hepatocellular Carcinoma
TL;DR: The pathogenesis and clinical relevance of MVI, which correlates with adverse biological features, including high grade, large tumor size, and epithelial–mesenchymal transition, are summarized.
Journal ArticleDOI
A Radiomics Nomogram for Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma.
Li Yang,Dongsheng Gu,Jingwei Wei,Chun Yang,Sheng-Xiang Rao,Wen-Tao Wang,Caizhong Chen,Ying Ding,Jie Tian,Mengsu Zeng +9 more
TL;DR: A radiomics nomogram incorporating clinicoradiological risk factors and radiomic features derived from HBP images achieved satisfactory preoperative prediction of the individualized risk of MVI in patients with HCC.
Journal ArticleDOI
Effect of Microvascular Invasion Risk on Early Recurrence of Hepatocellular Carcinoma After Surgery and Radiofrequency Ablation.
Sunyoung Lee,Sunyoung Lee,Tae Wook Kang,Kyoung Doo Song,Min Woo Lee,Hyunchul Rhim,Hyo Keun Lim,Hyo Keun Lim,So Yeon Kim,Dong Hyun Sinn,Jong Man Kim,Kyunga Kim,Kyunga Kim,Sang Yun Ha +13 more
TL;DR: The MVI prediction model predicted the risk of MVI in patients with a small HCC with high accuracy and patients with MVI who had undergone RFA were more vulnerable to recurrence than those who had underwent SR.
Journal ArticleDOI
A radiomics nomogram for preoperative prediction of microvascular invasion risk in hepatitis B virus-related hepatocellular carcinoma.
TL;DR: The radiomics nomogram, as a noninvasive preoperative prediction method, shows a favorable predictive accuracy for MVI status in patients with HBV-related HCC.
Journal ArticleDOI
Preoperative prediction of microvascular invasion in hepatocellular cancer: a radiomics model using Gd-EOB-DTPA-enhanced MRI
Shi-Ting Feng,Yingmei Jia,Bing Liao,Bingsheng Huang,Qian Zhou,Xin Li,Kaikai Wei,Lili Chen,Bin Li,Wei Wang,Shuling Chen,Xiaofang He,Haibo Wang,Sui Peng,Zebin Chen,Mimi Tang,Zhihang Chen,Yang Hou,Zhenwei Peng,Ming Kuang +19 more
TL;DR: An effective radiomics model for prediction of microvascular invasion in HCC patients is established and may therefore help clinicians make precise decisions regarding treatment before the surgery.
References
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Journal ArticleDOI
Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy
Hiroshi Imamura,Yutaka Matsuyama,Eiji Tanaka,Takao Ohkubo,Kiyoshi Hasegawa,Shinichi Miyagawa,Yasuhiko Sugawara,Masami Minagawa,Tadatoshi Takayama,Seiji Kawasaki,Masatoshi Makuuchi,Masatoshi Makuuchi +11 more
TL;DR: Variables associated with metastatic recurrence were factors to early phase recurrence; whereas those related with elevated carcinogenesis contributed to late phase recurrences, thus providing an epidemiological evidence that different mechanisms, i.e. metastasis and de novo, are involved in intrahepaticRecurrence after hepatectomy for HCC.
Journal ArticleDOI
Tumor size predicts vascular invasion and histologic grade: Implications for selection of surgical treatment for hepatocellular carcinoma
Timothy M. Pawlik,Keith A. Delman,Jean Nicolas Vauthey,David M. Nagorney,Irene Oi-Lin Ng,Iwao Ikai,Yoshio Yamaoka,Jacques Belghiti,Gregory Y. Lauwers,Ronnie T.P. Poon,Eddie K. Abdalla +10 more
TL;DR: In this article, the authors examined the relationship between HCC tumor size and microscopic vascular invasion and histologic grade in a multicenter international database of 1,073 patients who underwent resection of HCC.
Journal ArticleDOI
Tumor size predicts vascular invasion and histologic grade
Eddie K. Abdalla,Timothy M. Pawlik,Keith A. Delman,Nicolas Vauthey,David M. Nagorney,Irene Oi-Lin Ng,Yoshio Yamaoka,Iwao Ikai,Jacques Belghiti,Gregory Y. Lauwers,Ronnie T.P. Poon +10 more
TL;DR: The high incidence of occult vascular invasion and advanced histologic grade in HCC tumors larger than 5 cm, as well as biologic predictors of poor prognosis, should be considered before criteria for transplantation are expanded to include these patients.
Journal ArticleDOI
CT and MR Imaging Diagnosis and Staging of Hepatocellular Carcinoma: Part II. Extracellular Agents, Hepatobiliary Agents, and Ancillary Imaging Features
TL;DR: The second article of this two-part review discusses basic concepts of diagnosis and staging, reviews the diagnostic performance of CT and MR Imaging with extracellular contrast agents and of MR imaging with hepatobiliary contrast agents, and examines in depth the major and ancillary imaging features used in the diagnosis and characterization of HCC.
Journal ArticleDOI
Recurrence after liver resection for hepatocellular carcinoma: risk factors, treatment, and outcomes.
Shimul A. Shah,Sean P. Cleary,Alice C. Wei,Ilun Yang,Bryce R. Taylor,Alan W. Hemming,Bernard Langer,David R. Grant,Paul D. Greig,Steven Gallinger +9 more
TL;DR: Despite recurrences in >50% of patients, long-term survival can be achieved after resection of HCC, and intermediate and poor tumor differentiation and tumor size and number were significant predictors of disease-free survival.