Prevalence of Hyperuricemia and Gout in Mainland China from 2000 to 2014: A Systematic Review and Meta-Analysis.
TLDR
The prevalence of hyperuricemia and gout was high in mainland China and the subgroup analysis suggested that the geographical region, whether the residents dwell in urban or rural and coastal or inland areas, the economic level, and sex may be associated with prevalence.Abstract:
We systematically identified the prevalence of hyperuricemia and gout in mainland China and provided informative data that can be used to create appropriate local public health policies. Relevant articles from 2000 to 2014 were identified by searching 5 electronic databases: PubMed, Google Scholar, Chinese Wanfang, CNKI, and Chongqing VIP. All of the calculations were performed using the Stata 11.0 and SPSS 20.0 software. The eligible articles (n = 36; 3 in English and 33 in Chinese) included 44 studies (38 regarding hyperuricemia and 6 regarding gout). The pooled prevalence of hyperuricemia and gout was 13.3% (95% CI: 11.9%, 14.6%) and 1.1% (95% CI: 0.7%, 1.5%), respectively. Although publication bias was observed, the results did not change after a trim and fill test, indicating that that impact of this bias was likely insignificant. The prevalence of hyperuricemia and gout was high in mainland China. The subgroup analysis suggested that the geographical region, whether the residents dwell in urban or rural and coastal or inland areas, the economic level, and sex may be associated with prevalence.read more
Citations
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Hyperuricemia-Related Diseases and Xanthine Oxidoreductase (XOR) Inhibitors: An Overview
TL;DR: This review discusses the mechanism of uric acid homeostasis and alterations, updated prevalence, therapeutic outcomes, and molecular pathophysiology of hyperuricemia-related diseases, and summarize current discoveries in the development of new XOR inhibitors.
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Prevalence of hyperuricemia and the relationship between serum uric acid and obesity: A study on Bangladeshi adults.
Nurshad Ali,Rasheda Perveen,Shahnaz Rahman,Shakil Mahmood,Sadaqur Rahman,Shiful Islam,Tangigul Haque,Abu Hasan Sumon,Rahanuma Raihanu Kathak,Noyan Hossain Molla,Farjana Islam,Nayan Chandra Mohanto,Shaikh Mirja Nurunnabi,Shamim Ahmed,Mustafizur Rahman +14 more
TL;DR: A significant positive relationship between SUA and obesity among the Bangladeshi adults is indicated and routine measurement of SUA is recommended in obese individuals to prevent hyperuricemia and its related complications.
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Prevalence and correlates of hyperuricemia in the middle-aged and older adults in China
TL;DR: Its prevalence varied greatly according to demographic, socioeconomic, and geographic factors, and in males, being single, at a higher economic level, living in the Southwest China, smoking, obesity, diabetes, hypertension and dyslipidemia were all significant risk factors, but females living in North China and Northwest China were with a lower hyperuricemia prevalence than females in East China.
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From purines to purinergic signalling: molecular functions and human diseases.
Zhao Huang,Na Xie,Peter Illes,Peter Illes,Francesco Di Virgilio,Henning Ulrich,Henning Ulrich,Alexey Semyanov,Alexey Semyanov,Alexei Verkhratsky,Alexei Verkhratsky,Alexei Verkhratsky,Beáta Sperlágh,Shu-Guang Yu,Canhua Huang,Canhua Huang,Yong Tang +16 more
TL;DR: In this paper, a molecular understanding of molecular mechanisms of purinergic signalling provides new and exciting insights into the treatment of human diseases such as neurodegeneration, rheumatic immune diseases, inflammation, and cancer.
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Management of hyperuricemia through dietary polyphenols as a natural medicament: A comprehensive review
Arshad Mehmood,Lei Zhao,Chengtao Wang,Muhammad Nadeem,Ali Raza,Nawazish Ali,Amjad Abbas Shah +6 more
TL;DR: The current comprehensive review figure outs the use of dietary polyphenols as a natural remedy for the management of hyperuricemia and the sources, affiliated pathways, mode of actions and factors affecting their efficiency are deeply discussed in this article.
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