Open AccessJournal Article
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Commentaries
James H. Stein,Judith S. Currier,Nguyen Tran Hien,Jeremy Farrar,Peter Horby,Hua Wang,Zijian Feng,Yuelong Shu,Hongjie Yu,Lei Zhou,Rongqiang Zu,Yang Huai,Jie Dong,Changjun Bao,Le-ying Wen,Hong Wang,Peng Yang,Wei Zhao,Libo Dong,Minghao Zhou,Qiaohong Liao,Haitao Yang,Min Wang,Xiaojun Lu,Zhiyang Shi,Wei Wang,Ling Gu,Fengcai Zhu,Qun Li,Weidong Yin,Weizhong Yang,Dexin Li,Timothy M. Uyeki,Yu Wang +33 more
TLDR
Limited, non-sustained person-to-person transmission of H5N1 virus probably occurred in this family cluster of two individuals infected with highly pathogenic avian influenza A (H5n1) virus in Jiangsu Province, China.About:
This article is published in The Lancet.The article was published on 2008-01-01 and is currently open access. It has received 237 citations till now. The article focuses on the topics: Viral culture & Influenza A virus.read more
Citations
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Airborne transmission of influenza A/H5N1 virus between ferrets
Sander Herfst,Eefje J. A. Schrauwen,Martin Linster,Salin Chutinimitkul,Emmie de Wit,Vincent J. Munster,Erin M. Sorrell,Theo M. Bestebroer,David F. Burke,Derek J. Smith,Derek J. Smith,Derek J. Smith,Guus F. Rimmelzwaan,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +14 more
TL;DR: Avian A/H5N1 influenza viruses can acquire the capacity for airborne transmission between mammals without recombination in an intermediate host and therefore constitute a risk for human pandemic influenza.
Journal ArticleDOI
Epidemiology of Human Infections with Avian Influenza A(H7N9) Virus in China
Qun Li,Lei Zhou,Minghao Zhou,Zhiping Chen,Furong Li,Huanyu Wu,Nijuan Xiang,Enfu Chen,Fenyang Tang,Dayan Wang,Ling Meng,Zhiheng Hong,Wenxiao Tu,Yang Cao,Leilei Li,Fan Ding,Bo Liu,Mei Wang,Rongheng Xie,Rongbao Gao,Xiaodan Li,Tian Bai,Shumei Zou,Jun He,Jiayu Hu,Yangting Xu,Chengliang Chai,Shiwen Wang,Yongjun Gao,Lianmei Jin,Yanping Zhang,Huiming Luo,Hongjie Yu,Jianfeng He,Qi Li,Xianjun Wang,Lidong Gao,Xinghuo Pang,Guohua Liu,Yansheng Yan,Hui Yuan,Yuelong Shu,Weizhong Yang,Yu Wang,Fan Wu,Timothy M. Uyeki,Zijian Feng +46 more
TL;DR: Most persons with confirmed H7N9 virus infection had severe lower respiratory tract illness, were epidemiologically unrelated, and had a history of recent exposure to poultry.
Journal ArticleDOI
Prevention and Control of Seasonal Influenza with Vaccines.
Lisa A. Grohskopf,Leslie Z. Sokolow,Karen R. Broder,Sonja J Olsen,Ruth A. Karron,Daniel B. Jernigan,Joseph S. Bresee +6 more
TL;DR: In light of concerns regarding low effectiveness against influenza A(H1N1)pdm09 in the United States during the 2013-14 and 2015-16 seasons, ACIP makes the interim recommendation that live attenuated influenza vaccine (LAIV4) should not be used.
Journal ArticleDOI
Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study
Haiying Chen,Hui Yuan,Rongbao Gao,Jinxiang Zhang,Dayan Wang,Ying Xiong,Guoyin Fan,Fan Yang,Xiaodan Li,Jianfang Zhou,Shumei Zou,Lei Yang,Tao Chen,Libo Dong,Hong Bo,Xiang Zhao,Ye Zhang,Yu Lan,Tian Bai,Jie Dong,Qun Li,Shiwen Wang,Yanping Zhang,Hui Li,Tian Gong,Yong Shi,Xiansheng Ni,Jianxiong Li,Jun Zhou,Jiyi Fan,Jingwen Wu,Xianfeng Zhou,Maohong Hu,Jianguo Wan,Weizhong Yang,Dexin Li,Guizhen Wu,Zijian Feng,George F. Gao,Yu Wang,Qi Jin,Mingbin Liu,Yuelong Shu +42 more
TL;DR: The first human infection with a novel reassortant avian influenza A H10N8 virus is reported, which was isolated from a patient from Nanchang City, China and caused human infection and could have been associated with the death of a patient.
Journal ArticleDOI
Emerging infectious diseases in southeast Asia: regional challenges to control.
TL;DR: The reasons why Southeast Asia is at risk from emerging infectious diseases are complex as discussed by the authors, including population growth and movement, urbanisation, changes in food production, agriculture and land use, water and sanitation, and the effect of health systems through generation of drug resistance.
References
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Journal ArticleDOI
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
Menno D. de Jong,Cameron P. Simmons,Tran Tan Thanh,Vo Minh Hien,Gavin J. D. Smith,Tran Nguyen Bich Chau,Dang Minh Hoang,Nguyen Van Vinh Chau,Truong Huu Khanh,Vo Cong Dong,Phan Tu Qui,Bach Van Cam,Do Quang Ha,Yi Guan,J. S. Malik Peiris,Nguyen Tran Chinh,Tran Tinh Hien,Jeremy Farrar +17 more
TL;DR: The observations indicate that high viral load, and the resulting intense inflammatory responses, are central to influenza H5N1 pathogenesis and the focus of clinical management should be on preventing this intense cytokine response, by early diagnosis and effective antiviral treatment.
Journal ArticleDOI
Development of a Real-Time Reverse Transcriptase PCR Assay for Type A Influenza Virus and the Avian H5 and H7 Hemagglutinin Subtypes
Erica Spackman,Dennis A. Senne,T. J. Myers,Leslie L. Bulaga,Lindsey P. Garber,Michael L. Perdue,Kenton L. Lohman,Luke T. Daum,David L. Suarez +8 more
TL;DR: The sensitivity and specificity of the real-time PCR assay were directly compared with those of the current standard for detection of influenza virus: virus isolation in embryonated chicken eggs and hemagglutinin subtyping by hemagGLutination inhibition (HI) assay.
Journal ArticleDOI
Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus.
Kwok-Yung Yuen,Paul K.S. Chan,Malik Peiris,D. N. C. Tsang,Tak-Lun Que,Kennedy F. Shortridge,P. T. Cheung,W. K. To,E. T. F. Ho,R. Sung,A. F. B. Cheng +10 more
TL;DR: Avian Influenza A H5N1 virus causes human influenza-like illness with a high rate of complications in adults admitted to hospital, and rapid H5-subtype-specific laboratory diagnosis can be made by RT-PCR applied directly to clinical specimens.
Journal ArticleDOI
Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus
James Stevens,Ola Blixt,Terrence M. Tumpey,Jeffery K. Taubenberger,James C. Paulson,Ian A. Wilson +5 more
TL;DR: The hemagglutinin structure at 2.9 angstrom resolution, from a highly pathogenic Vietnamese H5N1 influenza virus, is more related to the 1918 and other human H1 HAs than to a 1997 duck H5 HA, which suggests a path for this H 5N1 virus to gain a foothold in the human population.
Journal ArticleDOI
Probable person-to-person transmission of avian influenza a (h5n1)
Kumnuan Ungchusak,Prasert Auewarakul,Scott F. Dowell,Rungrueng Kitphati,Wattana Auwanit,Pilaipan Puthavathana,Mongkol Uiprasertkul,Kobporn Boonnak,Chakrarat Pittayawonganon,Nancy J. Cox,Sherif R. Zaki,Pranee Thawatsupha,Malinee Chittaganpitch,Rotjana Khontong,James Mark Simmerman,Supamit Chunsutthiwat +15 more
TL;DR: Disease in the mother and aunt probably resulted from person-to-person transmission of this lethal avian influenzavirus during unprotected exposure to the critically ill index patient.
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