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Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.

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TLDR
Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy.
Abstract
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.

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Citations
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Modified CBT for social anxiety and social functioning in young adults with autism spectrum disorder.

TL;DR: In this paper, the authors evaluated the potential benefit, tolerability and acceptability of a group cognitive-behaviour therapy (CBT) intervention in adolescents and young adults with ASD.
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Stability of co-occurring psychiatric diagnoses in autistic men and women

TL;DR: This study provides quantitative estimates of the temporal stability of specific psychiatric conditions before and after a diagnosis of autism in adults.
Journal ArticleDOI

Conceptualising paranoia in ASD: A systematic review and development of a theoretical framework

TL;DR: The initial evidence indicates that paranoia in ASD may be linked with theory of mind performance, negative affect, and jumping to conclusions, but not to attributional style, and it is hypothesised that core ASD characteristics and associated neurocognitive impairments also serve to precipitate and perpetuate paranoia.
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Reconciling Dimensional and Categorical Models of Autism Heterogeneity: a Brain Connectomics & Behavioral Study

TL;DR: There exist at least three ASD factors with dissociable patterns of whole-brain RSFC, behaviors and demographics, and these factors differentiated between core ASD and comorbid symptoms - a less appreciated domain of heterogeneity in ASD.
Journal ArticleDOI

The health of college students on the autism spectrum as compared to their neurotypical peers.

TL;DR: It is found that students with autism reported poorer physical and mental health, more depressive symptoms, and more symptoms of anxiety even after taking into account other disabilities they may have experienced.
References
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Journal ArticleDOI

A Simple Sequentially Rejective Multiple Test Procedure

TL;DR: In this paper, a simple and widely accepted multiple test procedure of the sequentially rejective type is presented, i.e. hypotheses are rejected one at a time until no further rejections can be done.
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Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders

TL;DR: The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria.
Journal ArticleDOI

Emotion Circuits in the Brain

TL;DR: The field of neuroscience has, after a long period of looking the other way, again embraced emotion as an important research area, and much of the progress has come from studies of fear, and especially fear conditioning as mentioned in this paper.
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