Journal ArticleDOI
Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.
Gagan Joshi,Janet Wozniak,Carter R. Petty,Carter R. Petty,Mary Kate Martelon,Ronna Fried,Anela Bolfek,Amelia Kotte,Jonathan R. Stevens,Jonathan R. Stevens,Stephannie L. Furtak,Michelle Bourgeois,Janet Caruso,Ashley Caron,Joseph Biederman +14 more
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TLDR
Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy.Abstract:
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.read more
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The health status of adults on the autism spectrum
Lisa A. Croen,Ousseny Zerbo,Yinge Qian,Maria L. Massolo,Steve Rich,Stephen Sidney,Clarissa Kripke +6 more
TL;DR: Nearly all medical conditions were significantly more common in adults with autism, including immune conditions, gastrointestinal and sleep disorders, seizure, obesity, dyslipidemia, hypertension, and diabetes.
Journal ArticleDOI
Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis.
Meng-Chuan Lai,Caroline Kassee,Richard Besney,Sarah Bonato,Laura Hull,William Mandy,Peter Szatmari,Peter Szatmari,Stephanie H. Ameis,Stephanie H. Ameis +9 more
TL;DR: This systematic review and meta-analysis searched for publications between Jan 1, 1993, and Feb 1, 2019 in English or French that reported original research using an observational design on the prevalence of co-occurring mental health conditions in people with autism and reported confirmed clinical diagnoses of the co- Occurring conditions and autism using DSM or ICD criteria.
Journal ArticleDOI
Autism spectrum disorder
Catherine Lord,Traolach S. Brugha,Tony Charman,James C. Cusack,Guillaume Dumas,Thomas W. Frazier,Emily J.H. Jones,Rebecca M. Jones,Andrew Pickles,Matthew W. State,Julie Lounds Taylor,Jeremy Veenstra-VanderWeele +11 more
TL;DR: This Primer by Lord and colleagues reviews the epidemiology, mechanisms, clinical detection and treatment of autism and identifies the long-term needs of people with autism.
Journal ArticleDOI
College Students: Mental Health Problems and Treatment Considerations
TL;DR: By becoming familiar with the unique problems characteristic of the developmental stage and environment college students are in, practitioners will be able to better serve them.
Journal ArticleDOI
Identifying the lost generation of adults with autism spectrum conditions
Meng-Chuan Lai,Simon Baron-Cohen +1 more
TL;DR: In delineating differential diagnoses, true comorbidities, and overlapping behaviour with other psychiatric diagnoses, particular attention should be paid to anxiety, depression, obsessive-compulsive disorder, psychosis, personality disorders, and other neurodevelopmental disorders.
References
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Journal ArticleDOI
Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity
David J. Posey,David J. Posey,Michael G. Aman,L. Eugene Arnold,Yaser Ramadan,Andrea N. Witwer,Ronald L. Lindsay,Christopher J. McDougle,Naomi B. Swiezy,Arlene E. Kohn,James T. McCracken,Bhavik Shah,Pegeen Cronin,James J. McGough,Lisa Sea Yun Lee,Lawrence Scahill,Andrés Martin,Kathleen Koenig,Deirdre H. Carroll,Christopher Young,Allison Lancor,Elaine Tierney,Jaswinder K. Ghuman,N. González,Marco A. Grados,Benedetto Vitiello,Louise Ritz,Shirley Chuang,Mark Davies,James Robinson,Donald J. McMahon +30 more
TL;DR: Methylphenidate was often efficacious in treating hyperactivity associated with pervasive developmental disorders, but the magnitude of response was less than that seen in typically developing children with attention-deficit/hyperactivity disorder.
Journal ArticleDOI
Social and psychiatric functioning in adolescents with Asperger syndrome compared with conduct disorder.
TL;DR: Psychosocial functioning in 20 male adolescents with AS, defined according to current ICD-10 criteria, and a comparison group of 20male adolescents with severe conduct disorder are reported, finding severe impairments in practical social functioning.
Journal ArticleDOI
Comorbidity of Asperger syndrome: A preliminary report
TL;DR: Patients with AS diagnosed according to the ICD-10/DSM-IV criteria presented with symptoms of an additional psychiatric disorder at the time of evaluation or during the 2-year follow-up, while depression was the most common diagnosis in adolescents and adults.
Journal ArticleDOI
The Comorbidity of Pervasive Developmental Disorder and Attention Deficit Hyperactivity Disorder: Results of a Retrospective Chart Review
Sam Goldstein,Adam Schwebach +1 more
TL;DR: Results indicate that a subgroup of children with PDD displaying significant ADHD-like symptoms may in fact have ADHD thus warranting a comorbid diagnosis of ADHD, and the current exclusionary DSM-IV-TR criteria of making such a comorebid diagnosis should be considered.
Journal ArticleDOI
The Heavy Burden of Psychiatric Comorbidity in Youth with Autism Spectrum Disorders: A Large Comparative Study of a Psychiatrically Referred Population
Gagan Joshi,Carter R. Petty,Janet Wozniak,Aude Henin,Ronna Fried,Maribel Galdo,Meghan Kotarski,Sarah Walls,Joseph Biederman +8 more
TL;DR: Youth with ASD have high levels of psychiatric comorbidity and dysfunction comparable to the referred population of youth without ASD, and may be important targets for intervention.