Journal ArticleDOI
Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.
Gagan Joshi,Janet Wozniak,Carter R. Petty,Carter R. Petty,Mary Kate Martelon,Ronna Fried,Anela Bolfek,Amelia Kotte,Jonathan R. Stevens,Jonathan R. Stevens,Stephannie L. Furtak,Michelle Bourgeois,Janet Caruso,Ashley Caron,Joseph Biederman +14 more
TLDR
Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy.Abstract:
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.read more
Citations
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Beyond childhood: psychiatric comorbidities and social background of adults with Asperger syndrome.
TL;DR: In this paper, the authors investigated psychiatric comorbidities, psychiatric history, professional background, partnerships, and children in 50 adults with Asperger syndrome (34 men and 16 women) over a broad age range (20-62 years).
Journal ArticleDOI
Disrupted Cerebrocerebellar Intrinsic Functional Connectivity in Young Adults with High-Functioning Autism Spectrum Disorder: A Data-Driven, Whole-Brain, High-Temporal Resolution Functional Magnetic Resonance Imaging Study.
Sheeba Arnold Anteraper,Sheeba Arnold Anteraper,Xavier Guell,Xavier Guell,Anila M. D'Mello,Neha Joshi,Susan Whitfield-Gabrieli,Susan Whitfield-Gabrieli,Gagan Joshi,Gagan Joshi +9 more
TL;DR: The description of functional connectivity abnormalities reported in this study using whole-brain, data-driven analyses has the potential to crucially advance the development of ASD biomarkers, targets for therapeutic interventions, and neural predictors for measuring treatment response.
Journal ArticleDOI
Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults
Toru Fujioka,Keisuke Inohara,Yuko Okamoto,Yasuhiro Masuya,Makoto Ishitobi,Daisuke N. Saito,Minyoung Jung,Minyoung Jung,Sumiyoshi Arai,Sumiyoshi Arai,Yukiko Matsumura,Takashi X. Fujisawa,Takashi X. Fujisawa,Kosuke Narita,Katsuaki Suzuki,Kenji J. Tsuchiya,Norio Mori,Taiichi Katayama,Makoto Sato,Toshio Munesue,Hidehiko Okazawa,Hidehiko Okazawa,Akemi Tomoda,Akemi Tomoda,Yuji Wada,Yuji Wada,Hirotaka Kosaka,Hirotaka Kosaka +27 more
TL;DR: It is suggested that Gazefinder is potentially a valuable and easy-to-use tool for objectively measuring unique gaze patterns and discriminating between ASD and TD in male adolescents and adults.
Journal ArticleDOI
Living “in the zone”: hyperfocus in adult ADHD
TL;DR: This is the first study to comprehensively assess HF in adults with high ADHD symptomology and to present a means for assessing HF.
Journal ArticleDOI
Understanding anxiety in adults on the autism spectrum: An investigation of its relationship with intolerance of uncertainty, sensory sensitivities and repetitive behaviours.
Ye In Jane Hwang,Ye In Jane Hwang,Samuel R. C. Arnold,Samuel R. C. Arnold,Preeyaporn Srasuebkul,Julian N. Trollor +5 more
TL;DR: Intolerance of uncertainty was found to be a significant mediator between sensory sensitivities and anxiety, as well as between anxiety and insistence on sameness behaviours, which is an important factor to be considered in the conceptualisation and management of elevated rates of anxiety for adults on the autism spectrum.
References
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