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Journal ArticleDOI

Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.

TLDR
Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy.
Abstract
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.

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Citations
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Psychosocial Treatments Targeting Anxiety and Depression in Adolescents and Adults on the Autism Spectrum: Review of the Latest Research and Recommended Future Directions

TL;DR: This synthesis of treatment research related to anxiety and depression in adolescents and adults with autism spectrum disorder (ASD) focuses on the scientific support for various forms of psychosocial interventions, useful adaptations to standard interventions, and engagement of candidate therapeutic mechanisms.
Journal ArticleDOI

Sleep Patterns in Adults with a Diagnosis of High-Functioning Autism Spectrum Disorder.

TL;DR: These findings support the notion that problems related to sleep, in particular insomnia, continue into adulthood in individuals with high-functioning autism spectrum disorder.
Journal ArticleDOI

Classification of functioning and impairment: the development of ICF core sets for autism spectrum disorder.

TL;DR: The authors preview the process for developing ICF Core Sets for ASD, a collaboration with the World Health Organization and the ICF Research Branch, with the goal of providing useful standards for research and clinical practice and generating a common language for functioning and impairment in ASD in different areas of life and across the life span.
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A Systematic Review of the Rates of Depression in Children and Adults With High-Functioning Autism Spectrum Disorder

TL;DR: Examination of the phenomenology of depression in HF ASD linked to the development of psychometrically valid assessment measures would facilitate epidemiological studies, improve clinical case recognition, and inform treatments and interventions.
References
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Journal ArticleDOI

A Simple Sequentially Rejective Multiple Test Procedure

TL;DR: In this paper, a simple and widely accepted multiple test procedure of the sequentially rejective type is presented, i.e. hypotheses are rejected one at a time until no further rejections can be done.
Journal ArticleDOI

Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders

TL;DR: The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria.
Journal ArticleDOI

Emotion Circuits in the Brain

TL;DR: The field of neuroscience has, after a long period of looking the other way, again embraced emotion as an important research area, and much of the progress has come from studies of fear, and especially fear conditioning as mentioned in this paper.
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