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Journal ArticleDOI

Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.

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TLDR
Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy.
Abstract
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.

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Citations
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Journal ArticleDOI

The health status of adults on the autism spectrum

TL;DR: Nearly all medical conditions were significantly more common in adults with autism, including immune conditions, gastrointestinal and sleep disorders, seizure, obesity, dyslipidemia, hypertension, and diabetes.
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Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis.

TL;DR: This systematic review and meta-analysis searched for publications between Jan 1, 1993, and Feb 1, 2019 in English or French that reported original research using an observational design on the prevalence of co-occurring mental health conditions in people with autism and reported confirmed clinical diagnoses of the co- Occurring conditions and autism using DSM or ICD criteria.
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College Students: Mental Health Problems and Treatment Considerations

TL;DR: By becoming familiar with the unique problems characteristic of the developmental stage and environment college students are in, practitioners will be able to better serve them.
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Identifying the lost generation of adults with autism spectrum conditions

TL;DR: In delineating differential diagnoses, true comorbidities, and overlapping behaviour with other psychiatric diagnoses, particular attention should be paid to anxiety, depression, obsessive-compulsive disorder, psychosis, personality disorders, and other neurodevelopmental disorders.
References
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Journal ArticleDOI

Asperger's syndrome and autism: comparison of early history and outcome

TL;DR: There were no substantive, qualitative differences between the AS and autistic groups, indicating that AS should be considered a mild form of high‐functioning autism, and the inclusion of AS among the autistic spectrum of disorders has implications for aetiological studies and for prevalence estimates of the pervasive developmental disorders.
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Amygdala volume and nonverbal social impairment in adolescent and adult males with autism.

TL;DR: These findings best support a model of amygdala hyperactivity that could explain most volumetric findings in autism.
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Bipolar disorder, schizophrenia, and other psychotic disorders in adults with childhood onset AD/HD and/or autism spectrum disorders

TL;DR: Current diagnostic criteria have to be revised to acknowledge the comorbidity of bipolar and/or psychotic disorders in AD/HD and ASD.
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The presentation of anxiety in children with pervasive developmental disorders.

TL;DR: Similarities in anxiety symptom presentation and their association with psychotic symptoms in both children with and without PDD support the possibility of psychiatric comorbidity in the former and highlight the importance of continued investigation of source-specific syndromes in children with PDD.
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Obsessions and compulsions in Asperger syndrome and high-functioning autism.

TL;DR: Obsessions and compulsions are both common in adults with high-functioning ASD and are associated with significant levels of distress, with only somatic obsessions and repeating rituals being more common in the OCD group.
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